Emergence of the stem cell secretome in regenerative engineering

L Daneshmandi, S Shah, T Jafari, M Bhattacharjee… - Trends in …, 2020 - cell.com
The secretome is defined as the set of molecules and biological factors that are secreted by
cells into the extracellular space. In the past decade, secretome-based therapies have …

Polymeric hydrogels as mesenchymal stem cell secretome delivery system in biomedical applications

M Arifka, G Wilar, KM Elamin, N Wathoni - Polymers, 2022 - mdpi.com
Secretomes of mesenchymal stem cells (MSCs) have been successfully studied in
preclinical models for several biomedical applications, including tissue engineering, drug …

[HTML][HTML] Role of the CXCR4-SDF1-HMGB1 pathway in the directional migration of cells and regeneration of affected organs

N Haque, IM Fareez, LF Fong, C Mandal… - World Journal of Stem …, 2020 - ncbi.nlm.nih.gov
In recent years, several studies have reported positive outcomes of cell-based therapies
despite insufficient engraftment of transplanted cells. These findings have created a huge …

Combining HUMSC secretome and a conductive hydrogel enhances angiogenesis and electrical transmission at myocardial infarct sites to support cardiac repair

S He, L Long, Z Wang, W Liu, W Zhang, C Hu… - Chemical Engineering …, 2023 - Elsevier
The postinfarction myocardium is in an environment of ischemia and hypoxia, and the
damaged myocardium develops into scar tissue lacking electrical conductivity after a series …

Extracellular vesicles from stem and progenitor cells for cell-free regenerative therapy

N Haque, D Widera, V Govindasamy… - Current molecular …, 2022 - ingentaconnect.com
Cell-based regenerative therapies involving stem or progenitor cells are considered as
possible therapeutic modalities to treat non-communicable and degenerative diseases …

La rimodulazione della funzione visiva cellulo-mediata mediante Limoli retinal restoration technique

P Limoli, EM Vingolo, C Limoli… - OFTALMOLOGIA …, 2022 - iris.uniroma1.it
L'allungamento della vita media, in coesistenza con le patologie distrofiche della
neuroretina, determina ricadute negative sulla qualità della vita della popolazione …

for Osteoarthritis.” Regenerative Engineering and Translational Medicine, 2020.

S Shah, M Bhattacharjee, T Otsuka… - Development of a … - search.proquest.com
OA is a complex disease that affects not only the cartilage tissue but also the synovium and
subchondral bone. OA pathogenesis is characterized by synovitis, chronic degeneration of …

Specific Bioactive Factors and Application of Bioinformatics Tools for the Successful Use of Secretome and Extracellular Vesicles as Cell-Free Therapeutics

N Haque, NH Abu Kasim - Current Molecular Medicine, 2022 - ingentaconnect.com
In the last two decades, the in vitro regenerative potential of different types of stem cells,
including the mesenchymal stem cells (MSCs), has been extensively studied. Multi-lineage …