Integrins are considered the main cell-adhesion transmembrane receptors that play
multifaceted roles as extracellular matrix (ECM)-cytoskeletal linkers and transducers in …

Alzheimer's disease (AD) is a genetically complex and heterogeneous disorder with
multifaceted neuropathological features, including β-amyloid plaques, neurofibrillary …

Brain infiltration of peripheral immune cells and their interactions with brain-resident cells
may contribute to Alzheimer's disease (AD) pathology. To examine these interactions, in the …

Neurodegenerative diseases are progressive degenerative conditions characterized by the
functional deterioration and ultimate loss of neurons. These incurable and debilitating …

Introduction Neutrophil accumulation is a well-established feature of Alzheimer's disease
(AD) and has been linked to cognitive impairment by modulating disease-relevant …

Neurodegenerative diseases (NDDs) are incurable and debilitating conditions that result in
progressive degeneration and/or death of nerve cells in the central nervous system (CNS) …

Neutrophils (polymorphonuclear cells; PMNs) form a first line of defense against pathogens
and are therefore an important component of the innate immune response. As a result of …

Neurodegenerative diseases are closely related to inflammatory and autoimmune events,
suggesting that the dysregulation of the immune system is a key pathological factor. Both …

Background: Cerebrovascular disease is a common comorbidity in patients with Alzheimer's
disease (AD). It is believed to contribute additively to the cognitive impairment and to lower …

People with type 2 diabetes mellitus (T2DM) are at increased risk of mild cognitive
impairment and dementia. Systemic inflammation has been proposed as a common risk …