Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation

JAHR Claassen, DHJ Thijssen… - Physiological …, 2021 - journals.physiology.org
Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …

Cerebral autoregulation in stroke

P Castro, E Azevedo, F Sorond - Current atherosclerosis reports, 2018 - Springer
Abstract Purpose of Review Cerebral autoregulation (CA) is a mechanism that maintains
cerebral blood flow constant despite fluctuations in systemic arterial blood pressure. This …

Transcranial Doppler: a stethoscope for the brain‐neurocritical care use

C Robba, D Cardim, M Sekhon… - Journal of …, 2018 - Wiley Online Library
Transcranial Doppler (TCD) ultrasonography is a noninvasive bedside monitoring technique
that can evaluate cerebral blood flow hemodynamics in the intracranial arterial vasculature …

Aerobic training and mobilization early post-stroke: cautions and considerations

S Marzolini, AD Robertson, P Oh, JM Goodman… - Frontiers in …, 2019 - frontiersin.org
Knowledge gaps exist in how we implement aerobic exercise programs during the early
phases post-stroke. Therefore, the objective of this review was to provide evidence-based …

Sport-related concussion alters indices of dynamic cerebral autoregulation

AD Wright, JD Smirl, K Bryk, S Fraser… - Frontiers in …, 2018 - frontiersin.org
Sport-related concussion is known to affect a variety of brain functions. However, the impact
of this brain injury on cerebral autoregulation (CA) is poorly understood. Thus, the goal of …

Impact of cerebral autoregulation monitoring in cerebrovascular disease: a systematic review

M Al-Kawaz, SM Cho, RF Gottesman, JI Suarez… - Neurocritical care, 2022 - Springer
Cerebral autoregulation (CA) prevents brain injury by maintaining a relatively constant
cerebral blood flow despite fluctuations in cerebral perfusion pressure. This process is …

Further understanding of cerebral autoregulation at the bedside: possible implications for future therapy

J Donnelly, MJ Aries, M Czosnyka - Expert review of …, 2015 - Taylor & Francis
Cerebral autoregulation reflects the ability of the brain to keep the cerebral blood flow (CBF)
relatively constant despite changes in cerebral perfusion pressure. It is an intrinsic …

[HTML][HTML] Cerebral pressure autoregulation in brain injury and disorders–a review on monitoring, management, and future directions

TS Wettervik, M Fahlström, P Enblad, A Lewén - World neurosurgery, 2022 - Elsevier
The role of cerebral pressure autoregulation (CPA) in brain injury and disorders has gained
increased interest. The CPA is often disturbed as a consequence of acute brain injury, which …

Pathophysiologic differences in cerebral autoregulation after subarachnoid hemorrhage

GA Santos, N Petersen, AA Zamani, R Du, S LaRose… - Neurology, 2016 - AAN Enterprises
Objective: To understand the physiologic basis of impaired cerebral autoregulation in
subarachnoid hemorrhage (SAH) and its relationship to neurologic outcomes. Methods: The …

Optimal bispectral index level of sedation and cerebral oximetry in traumatic brain injury: a non-invasive individualized approach in critical care?

L Froese, A Gomez, AS Sainbhi, C Batson… - Intensive Care Medicine …, 2022 - Springer
Background Impaired cerebral autoregulation has been linked with worse outcomes, with
literature suggesting that current therapy guidelines fail to significantly impact …