Sulfur fluoride exchange (SuFEx), a new generation of click chemistry, was first presented by
Sharpless, Dong and co-workers in 2014. Owing to the high stability and yet efficient …

Click chemistry is a conceptual strategy to rapidly synthesize and discover functional
molecules. Sulfur fluoride exchange (SuFEx) is a click reaction that has revolutionized …

Sulfur fluoride exchange (SuFEx) has emerged as the new generation of click chemistry. We
report here a SuFEx-enabled, agnostic approach for the discovery and optimization of …

Abstract Sulfuryl fluoride, SO2F2, has been found to derivatize phenols in all kinds of
environments, even those in highly functional molecules. We now report that a solid …

Recent advances in the synthesis of sulfur (VI)-fluorides has enabled incredible growth in
their application in biomolecular chemistry. This review aims to serve as a primer …

Spectral stability of small-molecule fluorescent probes is required for correct interpretation
and reproducibility of multicolor fluorescence imaging data, in particular under high (de) …

Selective covalent modification of a targeted protein is a powerful tool in chemical biology
and drug discovery, with applications ranging from identification and characterization of …

A method to activate sulfamoyl fluorides, fluorosulfates, and sulfonyl fluorides with calcium
triflimide and DABCO for SuFEx with amines is described. The reaction was applied to a …

SuFEx reactions, in which an S− F moiety reacts with a silyl‐protected phenol, have been
developed as powerful click reactions. In the current paper we open up the potential of …

Sulfur (VI) fluoride exchange click chemistry is a formidable tool to rapidly and effectively link
chemical structures. Despite advances in the field in recent years, the installation of the …