In response to precision medicine: Current subcellular targeting strategies for cancer therapy
Emerging as a potent anticancer treatment, subcellular targeted cancer therapy has drawn
increasing attention, bringing great opportunities for clinical application. Here, two targeting …
increasing attention, bringing great opportunities for clinical application. Here, two targeting …
[HTML][HTML] A survey of multimodal information fusion for smart healthcare: Mapping the journey from data to wisdom
Multimodal medical data fusion has emerged as a transformative approach in smart
healthcare, enabling a comprehensive understanding of patient health and personalized …
healthcare, enabling a comprehensive understanding of patient health and personalized …
Molecular tumour boards—current and future considerations for precision oncology
AM Tsimberidou, M Kahle, HH Vo, MA Baysal… - Nature Reviews …, 2023 - nature.com
Over the past 15 years, rapid progress has been made in developmental therapeutics,
especially regarding the use of matched targeted therapies against specific oncogenic …
especially regarding the use of matched targeted therapies against specific oncogenic …
Tumor fraction correlates with detection of actionable variants across> 23,000 circulating tumor DNA samples
H Husain, DC Pavlick, BJ Fendler… - JCO Precision …, 2022 - ascopubs.org
PURPOSE Profiling of circulating tumor DNA (ctDNA) is increasingly adopted in the
management of solid tumors, concurrent with increased availability of more comprehensive …
management of solid tumors, concurrent with increased availability of more comprehensive …
Drug repurposing for viral cancers: A paradigm of machine learning, deep learning, and virtual screening‐based approaches
Cancer management is major concern of health organizations and viral cancers account for
approximately 15.4% of all known human cancers. Due to large number of patients, efficient …
approximately 15.4% of all known human cancers. Due to large number of patients, efficient …
Multicentric pilot study to standardize clinical whole exome sequencing (WES) for cancer patients
M Menzel, S Ossowski, S Kral, P Metzger… - NPJ Precision …, 2023 - nature.com
A growing number of druggable targets and national initiatives for precision oncology
necessitate broad genomic profiling for many cancer patients. Whole exome sequencing …
necessitate broad genomic profiling for many cancer patients. Whole exome sequencing …
[HTML][HTML] Predicting gene mutation status via artificial intelligence technologies based on multimodal integration (MMI) to advance precision oncology
J Shao, J Ma, Q Zhang, W Li, C Wang - Seminars in cancer biology, 2023 - Elsevier
Personalized treatment strategies for cancer frequently rely on the detection of genetic
alterations which are determined by molecular biology assays. Historically, these processes …
alterations which are determined by molecular biology assays. Historically, these processes …
[HTML][HTML] Access and quality of biomarker testing for precision oncology in Europe
N Normanno, K Apostolidis, A Wolf, R Al Dieri… - European journal of …, 2022 - Elsevier
Background Predictive biomarkers are essential for selecting the best therapeutic strategy in
patients with cancer. The International Quality Network for Pathology, the European Cancer …
patients with cancer. The International Quality Network for Pathology, the European Cancer …
Interpreting and integrating genomic tests results in clinical cancer care: Overview and practical guidance
R Casolino, PA Beer, D Chakravarty… - CA: a cancer journal …, 2024 - Wiley Online Library
The last decade has seen rapid progress in the use of genomic tests, including gene panels,
whole‐exome sequencing, and whole‐genome sequencing, in research and clinical cancer …
whole‐exome sequencing, and whole‐genome sequencing, in research and clinical cancer …
Precision medicine: affording the successes of science
Science has made remarkable advances in understanding the molecular basis of disease,
generating new and effective rationally-designed treatments at an accelerating rate …
generating new and effective rationally-designed treatments at an accelerating rate …