In response to precision medicine: Current subcellular targeting strategies for cancer therapy

Z Li, J Zou, X Chen - Advanced Materials, 2023 - Wiley Online Library
Emerging as a potent anticancer treatment, subcellular targeted cancer therapy has drawn
increasing attention, bringing great opportunities for clinical application. Here, two targeting …

[HTML][HTML] A survey of multimodal information fusion for smart healthcare: Mapping the journey from data to wisdom

T Shaik, X Tao, L Li, H Xie, JD Velásquez - Information Fusion, 2024 - Elsevier
Multimodal medical data fusion has emerged as a transformative approach in smart
healthcare, enabling a comprehensive understanding of patient health and personalized …

Molecular tumour boards—current and future considerations for precision oncology

AM Tsimberidou, M Kahle, HH Vo, MA Baysal… - Nature Reviews …, 2023 - nature.com
Over the past 15 years, rapid progress has been made in developmental therapeutics,
especially regarding the use of matched targeted therapies against specific oncogenic …

Tumor fraction correlates with detection of actionable variants across> 23,000 circulating tumor DNA samples

H Husain, DC Pavlick, BJ Fendler… - JCO Precision …, 2022 - ascopubs.org
PURPOSE Profiling of circulating tumor DNA (ctDNA) is increasingly adopted in the
management of solid tumors, concurrent with increased availability of more comprehensive …

Drug repurposing for viral cancers: A paradigm of machine learning, deep learning, and virtual screening‐based approaches

F Ahmed, IS Kang, KH Kim, A Asif… - Journal of Medical …, 2023 - Wiley Online Library
Cancer management is major concern of health organizations and viral cancers account for
approximately 15.4% of all known human cancers. Due to large number of patients, efficient …

Multicentric pilot study to standardize clinical whole exome sequencing (WES) for cancer patients

M Menzel, S Ossowski, S Kral, P Metzger… - NPJ Precision …, 2023 - nature.com
A growing number of druggable targets and national initiatives for precision oncology
necessitate broad genomic profiling for many cancer patients. Whole exome sequencing …

[HTML][HTML] Predicting gene mutation status via artificial intelligence technologies based on multimodal integration (MMI) to advance precision oncology

J Shao, J Ma, Q Zhang, W Li, C Wang - Seminars in cancer biology, 2023 - Elsevier
Personalized treatment strategies for cancer frequently rely on the detection of genetic
alterations which are determined by molecular biology assays. Historically, these processes …

[HTML][HTML] Access and quality of biomarker testing for precision oncology in Europe

N Normanno, K Apostolidis, A Wolf, R Al Dieri… - European journal of …, 2022 - Elsevier
Background Predictive biomarkers are essential for selecting the best therapeutic strategy in
patients with cancer. The International Quality Network for Pathology, the European Cancer …

Interpreting and integrating genomic tests results in clinical cancer care: Overview and practical guidance

R Casolino, PA Beer, D Chakravarty… - CA: a cancer journal …, 2024 - Wiley Online Library
The last decade has seen rapid progress in the use of genomic tests, including gene panels,
whole‐exome sequencing, and whole‐genome sequencing, in research and clinical cancer …

Precision medicine: affording the successes of science

CY Lu, V Terry, DM Thomas - NPJ Precision Oncology, 2023 - nature.com
Science has made remarkable advances in understanding the molecular basis of disease,
generating new and effective rationally-designed treatments at an accelerating rate …