This report reviews the literature on the genotoxicity of mainstream tobacco smoke and
cigarette smoke condensate (CSC) published since 1985. CSC is genotoxic in nearly all …

Environmental tobacco smoke (ETS), or second-hand smoke, is a widespread contaminant
of indoor air in environments where smoking is not prohibited. It is a significant source of …

The IARC Monographs series publishes authoritative independent assessments by
international experts of the carcinogenic risks posed to humans by a variety of agents …

Exposure to thirdhand smoke (THS) is a newly described health risk. Evidence supports its
widespread presence in indoor environments. However, its genotoxic potential, a critical …

Chlorophyllin, the sodium and copper salt of chlorophyll, was tested for its ability to inhibit
the mutagenic activity of a variety of complex mixtures—extracts of fried beef, fried shredded …

Epidemiological evidence suggests that smoking is a major cause of human lung cancer1,
2. However, the mechanism by which cigarette smoke induces the cancer remains obscure …

Human lung cancer exhibits a high frequency of transver-sion mutations at G: C base pairs
of the p53 gene, possibly the result of DNA damage by cigarette smoke constituents, most …

Bacground: Cigarette smoking may be a risk factor for leukemia. No detailed biological
mechanism has been proposed, but a causal link is made plausible by evidence os systemic …

A testing program was designed to evaluate the potential effects of 333 ingredients added to
typical commercial blended test cigarettes on selected biological and chemical endpoints …

Oral cancer, although uncommon in the Western world, accounts for up to 40% of all
malignancies in parts of India and South East Asia. Recognised aetiological agents of oral …