Synapses are the site for brain communication where information is transmitted between
neurons and stored for memory formation. Synaptic degeneration is a global and early …

The diagnosis of neurodegenerative disorders is often challenging due to the lack of
diagnostic tools, comorbidities and shared pathological manifestations. Synaptic dysfunction …

It is estimated that between 50% and 75% of all cases of dementia are due to Alzheimer's
disease (AD), the most common neurodegenerative disease among World population …

Alzheimer's disease (AD) is the most common form of dementia and cases are rising
worldwide. The effort to fight this disease is hampered by a lack of disease-modifying …

The global liquid biopsy industry is expected to exceed $ US5 billion by 2023. One
application of liquid biopsy technology is the diagnosis of disease using biomarkers found in …

In addition to amyloid and tau pathology in the central nervous system (CNS), inflammatory
processes and synaptic dysfunction are highly important mechanisms involved in the …

Objectives The hexanucleotide repeat expansion in the C9orf72 gene is the most common
mutation associated with amyotrophic lateral sclerosis (C9-ALS) and frontotemporal …

Glycosaminoglycan (GAG)–protein interactions mediate critical physiological and
pathological processes, such as neuronal plasticity, development, and viral invasion …

Aims: To evaluate H3K9 acetylation and gene expression profiles in three brain regions of
Alzheimer's disease (AD) patients and elderly controls, and to identify AD region-specific …

Lower cerebrospinal fluid (CSF) levels of neuronal pentraxin receptor (NPTXR) are
associated with Alzheimer's disease (AD), but few studies show longitudinal changes in CSF …