Throughout the body, the extracellular matrix (ECM) provides structure and organization to
tissues and also helps regulate cell migration and intercellular communication. In the injured …

It has been 50years since Gross and Lapiere discovered collagenolytic activity during
tadpole tail metamorphosis, which was later on revealed as MMP-1, the founding member of …

This review will focus on matrix metalloproteinases (MMPs) and their inhibitors in the context
of spinal cord injury (SCI). MMPs have a specific cellular and temporal pattern of expression …

Recently, matrix metalloproteinases (MMPs) are emerging as important molecules in
neuroinflammation as well as neuronal cell death. However, the role of MMPs in activated …

Spinal cord injury (SCI) triggers a well characterized, acute, local inflammation leading to
secondary damage at the lesion site. Another little recognized problem may be the activation …

The neurovascular unit, which consists of astrocytic end-feet, neurons, pericytes, and
endothelial cells, plays a key role in maintaining brain homeostasis by forming the blood …

Objectives This review summarizes recent developments in platelet biology relevant to
neuroinflammatory disorders. Multiple sclerosis (MS) is taken as the" Poster Child" of these …

Background Cerebral ischemia has been shown to induce activation of matrix
metalloproteinases (MMPs), particularly MMP-9, which is associated with impairment of the …

EphB receptors provide crucial adhesive and repulsive signals during cell migration and
axon guidance, but it is unclear how they switch between these opposing responses. Here …

Matrix metalloproteinases (MMPs) constitute a family of zinc‐dependent endopeptidases
that mediate extracellular matrix turnover and associated processes, such as cell survival …