Toll-like receptors, associated biological roles, and signaling networks in non-mammals

L Nie, SY Cai, JZ Shao, J Chen - Frontiers in immunology, 2018 - frontiersin.org
The innate immune system is the first line of defense against pathogens, which is initiated by
the recognition of pathogen-associated molecular patterns (PAMPs) and endogenous …

The two NF-κB pathways regulating bacterial and WSSV infection of shrimp

C Li, S Wang, J He - Frontiers in immunology, 2019 - frontiersin.org
The outbreak of diseases ordinarily results from the disruption of the balance and harmony
between hosts and pathogens. Devoid of adaptive immunity, shrimp rely largely on the …

Discovery of immune molecules and their crucial functions in shrimp immunity

A Tassanakajon, K Somboonwiwat, P Supungul… - Fish & shellfish …, 2013 - Elsevier
Several immune-related molecules in penaeid shrimps have been discovered, most of these
via the analysis of expressed sequence tag libraries, microarray studies and proteomic …

Recent advances in researches on the innate immunity of shrimp in China

F Li, J Xiang - Developmental & Comparative Immunology, 2013 - Elsevier
The annual production of shrimp culture in mainland of China has been over one million
tons for several years. The major cultivated penaeidae species are Litopenaeus vannamei …

Signaling pathways regulating innate immune responses in shrimp

F Li, J Xiang - Fish & shellfish immunology, 2013 - Elsevier
The first line of defense against microbial infections in animals is innate immune response
which triggers diverse humoral and cellular activities via signal transduction pathways. Toll …

Toll-like receptors (TLRs) in aquatic animals: signaling pathways, expressions and immune responses

PR Rauta, M Samanta, HR Dash, B Nayak, S Das - Immunology Letters, 2014 - Elsevier
The innate system's recognition of non-self and danger signals is mediated by a limited
number of germ-line encoded pattern recognition receptors (PRRs) that recognize pathogen …

Pattern recognition receptors acting in innate immune system of shrimp against pathogen infections

XW Wang, JX Wang - Fish & shellfish immunology, 2013 - Elsevier
Invertebrates, including shrimp, have developed very complicated innate immune system
against pathogens. Much work has been performed on the innate immunity of shrimp …

[HTML][HTML] RNAi screening identifies a new Toll from shrimp Litopenaeus vannamei that restricts WSSV infection through activating Dorsal to induce antimicrobial …

H Li, B Yin, S Wang, Q Fu, B Xiao, K Lǚ, J He… - PLoS …, 2018 - journals.plos.org
The function of Toll pathway defense against bacterial infection has been well established in
shrimp, however how this pathway responds to viral infection is still largely unknown. In this …

Research progress in innate immunity of freshwater crustaceans

Y Huang, Q Ren - Developmental & Comparative Immunology, 2020 - Elsevier
Invertebrates lack adaptive immunity and innate immunity plays important roles in combating
foreign invasive pathogens. Freshwater crustaceans, which are invertebrates, depend …

Molecular cloning, characterization and expression analysis of two novel Tolls (LvToll2 and LvToll3) and three putative Spätzle-like Toll ligands (LvSpz1–3) from …

PH Wang, JP Liang, ZH Gu, DH Wan, SP Weng… - Developmental & …, 2012 - Elsevier
Toll-like receptor-mediated NF-κB pathways are essential for inducing immune related-gene
expression in the defense against bacterial, fungal and viral infections in insects and …