Elevating chemistry research with a modern electronics toolkit

GRD Prabhu, PL Urban - Chemical Reviews, 2020 - ACS Publications
With the rapid development of high technology, chemical science is not as it used to be a
century ago. Many chemists acquire and utilize skills that are well beyond the traditional …

Applications of electrowetting-on-dielectric (EWOD) technology for droplet digital PCR

X Rui, S Song, W Wang, J Zhou - Biomicrofluidics, 2020 - pubs.aip.org
Digital microfluidics is an elegant technique based on single droplets for the design,
composition, and manipulation of microfluidic systems. In digital microfluidics, especially in …

Splitting of droplet with different sizes inside a symmetric T-junction microchannel using an electric field

K Fallah, E Fattahi - Scientific Reports, 2022 - nature.com
In the current study, droplets dynamics under an asymmetric electric field in a T-junction are
numerically studied using COMSOL Multi-physics software. The effect of different factors …

“One-to-three” droplet generation in digital microfluidics for parallel chemiluminescence immunoassays

K Jin, C Hu, S Hu, C Hu, J Li, H Ma - Lab on a Chip, 2021 - pubs.rsc.org
In digital microfluidics, droplet generation is a fundamental operation for quantitative liquid
manipulation. The generation of well-defined micro-droplets on a chip with restricted device …

Laser fabrication of modular superhydrophobic chips for reconfigurable assembly and self-propelled droplet manipulation

H Wang, YL Zhang, DD Han, W Wang, HB Sun - PhotoniX, 2021 - Springer
Natural creatures that enables controllable liquid transport provides the inspiration for
developing novel microfluidic devices by engineering functional surfaces with …

Sub-5-minute ultrafast PCR using digital microfluidics

L Wan, M Li, MK Law, PI Mak, RP Martins… - Biosensors and …, 2023 - Elsevier
The development of a rapid and reliable polymerase chain reaction (PCR) method for point-
of-care (POC) diagnosis is crucial for the timely identification of pathogens. Microfluidics …

Cancer drug screening with an on-chip multi-drug dispenser in digital microfluidics

J Zhai, C Li, H Li, S Yi, N Yang, K Miao, C Deng, Y Jia… - Lab on a Chip, 2021 - pubs.rsc.org
Microfluidics has been the most promising platform for drug screening with a limited number
of cells. However, convenient on-chip preparation of a wide range of drug concentrations …

A digital microfluidic system with 3D microstructures for single-cell culture

J Zhai, H Li, AHH Wong, C Dong, S Yi, Y Jia… - Microsystems & …, 2020 - nature.com
Despite the precise controllability of droplet samples in digital microfluidic (DMF) systems,
their capability in isolating single cells for long-time culture is still limited: typically, only a few …

Nucleic acid analysis on electrowetting-based digital microfluidics

R Shen, S Yi, P Wang, PI Mak, RP Martins… - TrAC Trends in Analytical …, 2023 - Elsevier
Since the disclosure of DNA/RNA as the genetic material, nucleic acid analysis has been an
indispensable category in molecular diagnosis, disease prediction, prognosis, and …

LampPort: a handheld digital microfluidic device for loop-mediated isothermal amplification (LAMP)

L Wan, J Gao, T Chen, C Dong, H Li, YZ Wen… - Biomedical …, 2019 - Springer
A major goal in the development of point-of-care (POC) devices is to build them as portable
to provide a rapid and effective determination for disease pathogens. In nucleic acid testing …