Deep learning methods for de novo peptide sequencing

W Bittremieux, V Ananth, WE Fondrie… - Mass Spectrometry …, 2024 - Wiley Online Library
Protein tandem mass spectrometry data are most often interpreted by matching observed
mass spectra to a protein database derived from the reference genome of the sample being …

A learned score function improves the power of mass spectrometry database search

V Ananth, J Sanders, M Yilmaz, B Wen, S Oh… - …, 2024 - academic.oup.com
Motivation One of the core problems in the analysis of protein tandem mass spectrometry
data is the peptide assignment problem: determining, for each observed spectrum, the …

Communicating mass spectrometry quality information in mzQC with Python, R, and Java

C Bielow, N Hoffmann… - Journal of the …, 2024 - ACS Publications
Mass spectrometry is a powerful technique for analyzing molecules in complex biological
samples. However, inter-and intralaboratory variability and bias can affect the data due to …

Detecting Human Contaminant Genetically Variant Peptides in Nonhuman Samples

F Chu, A Lin - Journal of Proteome Research, 2025 - ACS Publications
During proteomics data analysis, experimental spectra are searched against a user-defined
protein database consisting of proteins that are reasonably expected to be present in the …

[PDF][PDF] From data to discovery: The essential role of computational tools in proteomics

W Bittremieux - Proteomics.-Weinheim, 2024 - repository.uantwerpen.be
In the ever-evolving landscape of scientific inquiry, the saying “software is eating the world,”
popularized in Silicon Valley over a decade ago, rings truer than ever before. This aphorism …