Peripheral artery disease (PAD), secondary to atherosclerotic disease, is currently the
leading cause of morbidity and mortality in the western world. While PAD is common, it is …

Veno-arterial extracorporeal membrane oxygenation (VA ECMO) is an increasingly adopted
life-saving mechanical circulatory support for a number of potentially reversible or treatable …

Guideline Summary Chronic limb-threatening ischemia (CLTI) is associated with mortality,
amputation, and impaired quality of life. These Global Vascular Guidelines (GVG) are …

Advances in endovascular therapies during the past decade have broadened the options for
treating peripheral vascular disease percutaneously. Endovascular treatment offers a lower …

Peripheral artery disease affects around 13% of the Western population who are more than
50 years old. 1 It is most commonly due to atherosclerosis, where an atherosclerotic plaque …

Critical limb ischemia (CLI) continues to be a significantly morbid disease process for the
aging population. Rigid guidelines for the management of patients with CLI are …

Nonstent-based local drug delivery during percutaneous intervention offers potential for
sustained antirestenotic efficacy without the limitations of permanent vascular implants …

Past decades have witnessed a major epidemiologic transition with a considerable increase
in the disease burden associated with atherosclerotic cardiovascular diseases (CVDs), with …

Molecular oxygen (O2) and carbon dioxide (CO2) are the primary gaseous substrate and
product of oxidative phosphorylation in respiring organisms, respectively. Variance in the …

Critical limb ischemia (CLI) is a clinical syndrome of ischemic pain at rest or tissue loss, such
as nonhealing ulcers or gangrene, related to peripheral artery disease. CLI has a high short …