Phenotypical and functional specialization of FOXP3+ regulatory T cells

DJ Campbell, MA Koch - Nature Reviews Immunology, 2011 - nature.com
Abstract Forkhead box P3 (FOXP3)+ regulatory T (TReg) cells prevent autoimmune disease,
maintain immune homeostasis and modulate immune responses during infection. To …

Regulatory T‐cell homeostasis: steady‐state maintenance and modulation during inflammation

KS Smigiel, S Srivastava, JM Stolley… - Immunological …, 2014 - Wiley Online Library
Regulatory T (Treg) cells play a vital role in the prevention of autoimmunity and the
maintenance of self‐tolerance, but these cells also have an active role in inhibiting immune …

Skin infection generates non-migratory memory CD8+ TRM cells providing global skin immunity

X Jiang, RA Clark, L Liu, AJ Wagers, RC Fuhlbrigge… - Nature, 2012 - nature.com
Protective T-cell memory has long been thought to reside in blood and lymph nodes, but
recently the concept of immune memory in peripheral tissues mediated by resident memory …

Organ-specific and memory treg cells: specificity, development, function, and maintenance

IK Gratz, DJ Campbell - Frontiers in immunology, 2014 - frontiersin.org
Foxp3+ regulatory T cells (Treg cells) are essential for establishing and maintaining self-
tolerance, and also inhibit immune responses to innocuous environmental antigens …

Advances in atopic dermatitis

N Novak, DYM Leung - Current opinion in immunology, 2011 - Elsevier
Atopic dermatitis (AD) results from barrier defects combined with modified immune
responses of the innate and the adaptive immune system to exogenous and endogenous …

IL-21 restricts virus-driven Treg cell expansion in chronic LCMV infection

I Schmitz, C Schneider, A Fröhlich, H Frebel… - PLoS …, 2013 - journals.plos.org
Foxp3+ regulatory T (Treg) cells are essential for the maintenance of immune homeostasis
and tolerance. During viral infections, Treg cells can limit the immunopathology resulting …

Skin viral infections: host antiviral innate immunity and viral immune evasion

V Lei, AJ Petty, AR Atwater, SA Wolfe… - Frontiers in …, 2020 - frontiersin.org
The skin is an active immune organ that functions as the first and largest site of defense to
the outside environment. Serving as the primary interface between host and pathogen, the …

Autoimmune diseases: role of steroid hormones

M Benagiano, P Bianchi, MM D'Elios, I Brosens… - Best Practice & …, 2019 - Elsevier
Autoimmune diseases (AIDs) are a heterogeneous group of disorders in terms of clinical
manifestations, pathogenesis, and prevalence, and there is no agreement to date on a …

Eczema vaccinatum

JL Reed, DE Scott, M Bray - Clinical infectious diseases, 2012 - academic.oup.com
Eczema vaccinatum (EV) is a complication of smallpox vaccination that can occur in persons
with eczema/atopic dermatitis (AD), in which vaccinia virus disseminates to cause an …

Smallpox vaccine safety is dependent on T cells and not B cells

SN Gordon, V Cecchinato, V Andresen… - Journal of Infectious …, 2011 - academic.oup.com
Abstract (See the editorial commentary by Bray, on pages 1037–9.) The licensed smallpox
vaccine, ACAM2000, is a cell culture derivative of Dryvax. Both ACAM2000 and Dryvax are …