Development of circulating microRNA-based biomarkers for medical decision-making: a friendly reminder of what should NOT be done

P Lakkisto, LT Dalgaard, T Belmonte… - Critical Reviews in …, 2023 - Taylor & Francis
Circulating cell-free microRNAs (miRNAs) represent a major reservoir for biomarker
discovery. Unfortunately, their implementation in clinical practice is limited due to a profound …

[HTML][HTML] Quantification of circulating microRNAs by droplet digital PCR for cancer detection

PDR Cirillo, K Margiotti, A Mesoraca… - BMC Research Notes, 2020 - Springer
Objective Circulating cell-free microRNAs (miRNAs) which consist of short-sequence RNAs
are released from cells into the blood stream and has emerged as new biomarkers in the …

MicroRNA expression profiling with a droplet digital PCR assay enables molecular diagnosis and prognosis of cancers of unknown primary

N Laprovitera, M Riefolo, E Porcellini… - Molecular …, 2021 - Wiley Online Library
Metastasis is responsible for the majority of cancer‐related deaths. Particularly, challenging
is the management of metastatic cancer of unknown primary site (CUP), whose tissue of …

Molecular testing on bronchial washings for the diagnosis and predictive assessment of lung cancer

R Roncarati, L Lupini, E Miotto, E Saccenti… - Molecular …, 2020 - Wiley Online Library
Cytopathological analyses of bronchial washings (BWs) collected during fibre‐optic
bronchoscopy are often inconclusive for lung cancer diagnosis. To address this issue, we …

[HTML][HTML] Multi-analytical test based on serum miRNAs and proteins quantification for ovarian cancer early detection

PDR Cirillo, K Margiotti, M Fabiani, MC Barros-Filho… - PLoS …, 2021 - journals.plos.org
Advanced ovarian cancer is one of the most lethal gynecological tumor, mainly due to late
diagnoses and acquired drug resistance. MicroRNAs (miRNAs) are small-non coding RNA …

[HTML][HTML] Circulating miR-184 is a potential predictive biomarker of cardiac damage in Anderson–Fabry disease

I Salamon, E Biagini, P Kunderfranco… - Cell Death & …, 2021 - nature.com
Enzyme replacement therapy (ERT) is a mainstay of treatment for Anderson–Fabry disease
(AFD), a pathology with negative effects on the heart and kidneys. However, no reliable …

[HTML][HTML] Cancer site-specific multiple microRNA quantification by droplet digital PCR

N Laprovitera, M Grzes, E Porcellini… - Frontiers in oncology, 2018 - frontiersin.org
Archival formalin-fixed paraffin-embedded (FFPE) tissues represent an extraordinary source
of smallRNAs, including microRNAs (miRNAs). Contrary to other RNA molecules, miRNAs …

[HTML][HTML] Plasma microrna quantification protocol

S Maiocchi, EN Collins, AR Peterson, KC Alexander… - Vessel plus, 2023 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate translation and are
involved in many pathological processes. They have emerged as promising biomarkers for …

Reconsidering neurogenetic indication in the human brain: Broad expression of doublecortin transcript in hippocampal and cortical cell populations

M Kim, TH Cho, SH Kim, JE Lee, SH Kim, HJ Kim… - 2024 - researchsquare.com
Adult neurogenesis may help overcome Alzheimer's disease; however, knowledge
concerning neurogenic markers in the human brain remains limited. Herein, we compared …

Molecular diagnosis and prognosis of cancers of unknown-primary (CUPs): progress from a microRNA-based droplet digital PCR assay

N Laprovitera, M Riefolo, E Porcellini, G Durante… - bioRxiv, 2021 - biorxiv.org
Metastasis is responsible for the majority of cancer-related deaths. Particularly challenging
is the management of metastatic cancer of unknown primary site (CUP), whose tissue-of …