From point-of-care testing to eHealth diagnostic devices (eDiagnostics)

DC Christodouleas, B Kaur, P Chorti - ACS Central Science, 2018 - ACS Publications
Point-of-care devices were originally designed to allow medical testing at or near the point of
care by health-care professionals. Some point-of-care devices allow medical self-testing at …

[HTML][HTML] Electrochemical detection of viruses and antibodies: A mini review

MR de Eguilaz, LR Cumba, RJ Forster - Electrochemistry communications, 2020 - Elsevier
Near patient detection of viral infection represents a powerful approach for the control of
emerging threats to global health. Moreover, the ability to identify individuals who have …

Blood drop patterns: Formation and applications

R Chen, L Zhang, D Zang, W Shen - Advances in colloid and interface …, 2016 - Elsevier
The drying of a drop of blood or plasma on a solid substrate leads to the formation of
interesting and complex patterns. Inter-and intra-cellular and macromolecular interactions in …

Integrated point-of-care molecular diagnostic devices for infectious diseases

W Liu, F Yue, LP Lee - Accounts of chemical research, 2021 - ACS Publications
Conspectus The global outbreaks of deadly infectious diseases caused by pathogenic
microorganisms have threatened public health worldwide and significantly motivated …

Micro total analysis systems: fundamental advances and applications

DEW Patabadige, S Jia, J Sibbitts, J Sadeghi… - Analytical …, 2016 - ACS Publications
It has been 14 years since the inaugural microfluidics review in Analytical Chemistry was
published. 1 The first papers describing these devices which are also commonly referred to …

Microfluidic sample preparation for medical diagnostics

F Cui, M Rhee, A Singh, A Tripathi - Annual review of biomedical …, 2015 - annualreviews.org
Fast and reliable diagnoses are invaluable in clinical care. Samples (eg, blood, urine, and
saliva) are collected and analyzed for various biomarkers to quickly and sensitively assess …

Microfluidic blood plasma separation for medical diagnostics: is it worth it?

WS Mielczarek, EA Obaje, TT Bachmann… - Lab on a Chip, 2016 - pubs.rsc.org
Circulating biomarkers are on the verge of becoming powerful diagnostic tools for various
human diseases. However, the complex sample composition makes it difficult to detect …

Vacuum-driven power-free microfluidics utilizing the gas solubility or permeability of polydimethylsiloxane (PDMS)

L Xu, H Lee, D Jetta, KW Oh - Lab on a Chip, 2015 - pubs.rsc.org
Suitable pumping methods for flow control remain a major technical hurdle in the path of
biomedical microfluidic systems for point-of-care (POC) diagnostics. A vacuum-driven power …

A high-efficiency superhydrophobic plasma separator

C Liu, SC Liao, J Song, MG Mauk, X Li, G Wu, D Ge… - Lab on a Chip, 2016 - pubs.rsc.org
To meet stringent limit-of-detection specifications for low abundance target molecules, a
relatively large volume of plasma is needed for many blood-based clinical diagnostics …

Capillary flow-driven microfluidic device with wettability gradient and sedimentation effects for blood plasma separation

MS Maria, PE Rakesh, TS Chandra, AK Sen - Scientific reports, 2017 - nature.com
We report a capillary flow-driven microfluidic device for blood-plasma separation that
comprises a cylindrical well between a pair of bottom and top channels. Exposure of the well …