Pharmacological effects and mechanisms of bee venom and its main components: Recent progress and perspective

P Shi, S Xie, J Yang, Y Zhang, S Han, S Su… - Frontiers in …, 2022 - frontiersin.org
Bee venom (BV), a type of defensive venom, has been confirmed to have favorable
activities, such as anti-tumor, neuroprotective, anti-inflammatory, analgesic, anti-infectivity …

Protein and Peptide‐Based Nanotechnology for Enhancing Stability, Bioactivity, and Delivery of Anthocyanins

L Zhang, L Yao, F Zhao, A Yu, Y Zhou… - Advanced …, 2023 - Wiley Online Library
Anthocyanin, a unique natural polyphenol, is abundant in plants and widely utilized in
biomedicine, cosmetics, and the food industry due to its excellent antioxidant, anticancer …

Efficient synthesis and anticancer evaluation of spider toxin peptide LVTX-8-based analogues with enhanced stability

QN Chi, SX Jia, H Yin, LE Wang, XY Fu, YN Ma… - Bioorganic …, 2023 - Elsevier
Cytotoxic peptides derived from spider venoms have been considered as promising
candidates for anticancer treatment. The novel cell penetrating peptide LVTX-8, which is a …

Targeting nanoparticles to malignant tumors

N Sharma, K Bietar, U Stochaj - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Nanomaterials are at the forefront of health research and development. Among different
nanomaterials, nanoparticles are especially promising for cancer theranostics. However …

Assembling p53 Activating Peptide With CeO2 Nanoparticle to Construct a Metallo-Organic Supermolecule Toward the Synergistic Ferroptosis of Tumor

J Wang, W Yang, X He, Z Zhang… - Frontiers in Bioengineering …, 2022 - frontiersin.org
Inducing lipid peroxidation and subsequent ferroptosis in cancer cells provides a potential
approach for anticancer therapy. However, the clinical translation of such therapeutic agents …

[HTML][HTML] Paracelsus' legacy in the faunal realm: Drugs deriving from animal toxins

T Fischer, R Riedl - Drug discovery today, 2022 - Elsevier
Given the vast number of venomous and poisonous animals, it is surprising that only
relatively few animal-derived toxins have been explored and made their way into marketed …

One new acid-activated hybrid anticancer peptide by coupling with a desirable ph-sensitive anionic partner peptide

L Chang, X Wu, K Ran, Y Tian, X Ouyang, H Liu… - ACS …, 2023 - ACS Publications
Anticancer peptides (ACPs) are promising antitumor resources, and developing acid-
activated ACPs as more effective and selective antitumor drugs would represent new …

Current advances in cell therapeutics: A biomacromolecules application perspective

SA Adeyemi, YE Choonara - Expert Opinion on Drug Delivery, 2022 - Taylor & Francis
Introduction Many chronic diseases have evolved and to circumvent the limitations of using
conventional drug therapies, smart cell encapsulating delivery systems have been explored …

Bioactive peptides from venoms against glioma progression

B Majc, M Novak, TT Lah, I Križaj - Frontiers in Oncology, 2022 - frontiersin.org
Venoms are complex mixtures of different molecules and ions. Among them, bioactive
peptides have been found to affect cancer hallmarks, such as cell proliferation, cell invasion …

Rational design of a new short anticancer peptide with good potential for cancer treatment

X Wu, Y Tian, K Ran, J Yao, Y Wang, X Ouyang… - European Journal of …, 2024 - Elsevier
Anticancer peptides (ACPs) have regarded as a new generation of promising antitumor
drugs due to the unique mode of action. The main challenge is to develop potential …