Potential and limitations of Klebsiella pneumoniae as a microbial cell factory utilizing glycerol as the carbon source

V Kumar, S Park - Biotechnology advances, 2018 - Elsevier
Klebsiella pneumoniae is a Gram-negative facultative anaerobe that metabolizes glycerol
efficiently under both aerobic and anaerobic conditions. This microbe is considered an …

Recent advances, challenges and metabolic engineering strategies in the biosynthesis of 3‐hydroxypropionic acid

B Liang, G Sun, X Zhang, Q Nie… - Biotechnology and …, 2022 - Wiley Online Library
As an attractive and valuable platform chemical, 3‐hydroxypropionic acid (3‐HP) can be
used to produce a variety of industrially important commodity chemicals and biodegradable …

Production of 3-hydroxypropionic acid from renewable substrates by metabolically engineered microorganisms: a review

X Wang, Z Cui, X Sun, Z Wang, T Chen - Molecules, 2023 - mdpi.com
3-Hydroxypropionic acid (3-HP) is a platform chemical with a wide range of existing and
potential applications, including the production of poly (3-hydroxypropionate)(P-3HP), a …

Optimum Rebalancing of the 3-Hydroxypropionic Acid Production Pathway from Glycerol in Escherichia coli

HG Lim, MH Noh, JH Jeong, S Park… - ACS synthetic …, 2016 - ACS Publications
3-Hydroxypropionic acid (3-HP) can be biologically produced from glycerol by two
consecutive enzymatic reactions, dehydration of glycerol to 3-hydroxypropionaldehyde (3 …

Production of 3-hydroxypropanoic acid from glycerol by metabolically engineered bacteria

C Jers, A Kalantari, A Garg, I Mijakovic - Frontiers in Bioengineering …, 2019 - frontiersin.org
3-hydroxypropanoic acid (3-HP) is a valuable platform chemical with a high demand in the
global market. 3-HP can be produced from various renewable resources. It is used as a …

Strain engineering for microbial production of value-added chemicals and fuels from glycerol

AW Westbrook, D Miscevic, S Kilpatrick… - Biotechnology …, 2019 - Elsevier
While the widespread reliance on fossil fuels is driven by their low cost and relative
abundance, this fossil-based economy has been deemed unsustainable and, therefore, the …

Co-production of hydrogen and ethanol from glucose in Escherichia coli by activation of pentose-phosphate pathway through deletion of phosphoglucose isomerase (pgi) and …

B Sundara Sekar, E Seol, S Park - Biotechnology for biofuels, 2017 - Springer
Abstract Background Biologically, hydrogen (H 2) can be produced through dark
fermentation and photofermentation. Dark fermentation is fast in rate and simple in reactor …

Characterization of an Entner–Doudoroff pathway-activated Escherichia coli

YE Kim, KH Cho, I Bang, CH Kim, YS Ryu… - … for Biofuels and …, 2022 - Springer
Background Escherichia coli have both the Embden–Meyerhof–Parnas pathway (EMPP)
and Entner–Doudoroff pathway (EDP) for glucose breakdown, while the EDP primarily …

Development of Pseudomonas asiatica as a host for the production of 3-hydroxypropionic acid from glycerol

TT Nguyen, S Lama, SK Ainala… - Bioresource …, 2021 - Elsevier
Pseudomonas asiatica C1, which could grow on glucose and aerobically synthesize
coenzyme B 12, was isolated and developed as a microbial cell factory for the production of …

Co-production of hydrogen and ethanol by pfkA-deficient Escherichia coli with activated pentose-phosphate pathway: reduction of pyruvate accumulation

B Sundara Sekar, E Seol, S Mohan Raj… - Biotechnology for Biofuels, 2016 - Springer
Background Fermentative hydrogen (H 2) production suffers from low carbon-to-H 2 yield, to
which problem, co-production of ethanol and H 2 has been proposed as a solution. For …