Abstract p70 S6 kinase (p70 S6K) is best known for its regulatory roles in protein synthesis
and cell growth by phosphorylating its primary substrate, ribosomal protein S6, upon …

Ribosomal protein S6 kinases belong to a family of highly conserved enzymes in eukaryotes
that regulate cell growth, proliferation, survival, and the stress response. It is well established …

As a person who has had a long scientific career in Ukraine, both before and after its re-
acquisition of independence thirty years ago, I would like to share my observations with the …

Ribosomal protein kinase S6 (S6K1) is one of the key components of the PI3K/mTOR/S6K1-
dependent signaling cascade, which plays an important role in the regulation of translation …

Aim. To generate and characterize MCF-7 cell lines with altered expression of p85, p70 and
p60 S6K1 isoforms: p85-/p70-/p60-MCF-7 and p85-/p70-/p60+ MCF-7. Methods …

Aim. To evaluate an impact of different S6K1 isoforms expression in MCF-7 cells on initiation
of Epithelial to Mesenchymal Transition (EMT). Methods. Immunocytochemical analysis …

Кіназа рибосомного білка S6 (S6K1) є одним із ключових компонентів PI3K/mTOR/S6K1-
залежного сигнального каскаду, який відіграє важливу роль в регуляції трансляції …

Aim. The purpose of the study was to generate and characterize anti-hER polyclonal
antibodies for elucidation of functional relationships between isoforms of estrogen receptor …

ABSTRACT Elongation factor P (EF-P) and its eukaryotic homolog eIF5A are auxiliary
translation factors that facilitate peptide bond formation when several sequential proline …

Мета: Оцінити вплив експресії різних ізоформ S6K1 у клітинах MCF-7 на ініціацію ЕМТ.
Методи: Імуноцитохімічний аналіз, ПЛР у реальному часі, Вестерн-блот. Результати …