[HTML][HTML] Cerebral small vessel disease: A review

J Chojdak-Łukasiewicz, E Dziadkowiak… - … in Clinical and …, 2021 - advances.umw.edu.pl
Cerebral small vessel disease (CSVD) is the most common, chronic and progressive
vascular disease. The changes affect arterioles, capillaries and small veins supplying the …

CADASIL in Greece: mutational spectrum and clinical characteristics based on a systematic review and pooled analysis of published cases

GP Paraskevas, MI Stefanou… - European Journal of …, 2022 - Wiley Online Library
Background Differences have been noted in the clinical presentation and mutational
spectrum of CADASIL among various geographical areas. The aim of the present study was …

Phenotypic variability in 446 CADASIL patients: Impact of NOTCH3 gene mutation location in addition to the effects of age, sex and vascular risk factors

C Dupé, S Guey, L Biard, S Dieng… - Journal of Cerebral …, 2023 - journals.sagepub.com
The recent discovery that the prevalence of cysteine mutations in the NOTCH3 gene
responsible for CADASIL was more than 100 times higher in the general population than …

Genetic spectrum of NOTCH3 and clinical phenotype of CADASIL patients in different populations

W Ni, Y Zhang, L Zhang, JJ Xie, HF Li… - CNS neuroscience & …, 2022 - Wiley Online Library
Introduction Cerebral autosomal‐dominant arteriopathy with subcortical infarcts and
leukoencephalopathy (CADASIL) is a relatively common cerebral small vessel disease …

Pro‐Hemorrhagic Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy Associated with NOTCH3 p.R75P Mutation with …

H Ishiyama, H Kim, S Saito, S Takeda… - Annals of …, 2024 - Wiley Online Library
Objectives Intracerebral hemorrhage (ICH) and cerebral microbleeds (CMB) in cerebral
autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy are …

NOTCH3 Variants and Genotype-Phenotype Features in Chinese CADASIL Patients

Y Hu, Q Sun, Y Zhou, F Yi, H Tang, L Yao, Y Tian… - Frontiers in …, 2021 - frontiersin.org
Cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy (CADASIL) is a cerebral small vessel disease caused by mutations in …

Lifelong cerebrovascular disease burden among CADASIL patients: analysis from a global health research network

AP Pan, T Potter, A Bako, J Tannous… - Frontiers in …, 2023 - frontiersin.org
Introduction Data reporting on patients with Cerebral Autosomal Dominant Arteriopathy with
Subcortical Infarcts and Leukoencephalopathy (CADASIL) within the United States …

Microbleed clustering in thalamus sign in CADASIL patients with NOTCH3 R75P mutation

J Takei, Y Higuchi, M Ando, A Yoshimura… - Frontiers in …, 2023 - frontiersin.org
Background and objective Cerebral autosomal dominant arteriopathy with subcortical
infarcts and leukoencephalopathy (CADASIL) is an inherited cerebral microvascular disease …

[HTML][HTML] Phenotypes Associated with NOTCH3 Cysteine-Sparing Mutations in Patients with Clinical Suspicion of CADASIL: A Systematic Review

Y Cao, DD Zhang, F Han, N Jiang, M Yao… - International Journal of …, 2024 - mdpi.com
CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy) is caused by NOTCH3 mutations affecting the number of cysteines …

Mutant NOTCH3ECD Triggers Defects in Mitochondrial Function and Mitophagy in CADASIL Cell Models

W Wang, Z Gong, Y Wang, Y Zhao… - Journal of …, 2024 - journals.sagepub.com
Background: Cerebral autosomal-dominant arteriopathy with subcortical infarction and
leukoencephalopathy (CADASIL) is an inherited small-vessel disease that affects the white …