Bioactive synthetic polymers

K Jung, N Corrigan, EHH Wong, C Boyer - Advanced Materials, 2022 - Wiley Online Library
Synthetic polymers are omnipresent in society as textiles and packaging materials, in
construction and medicine, among many other important applications. Alternatively, natural …

[HTML][HTML] Hydrophilic polymers: Current trends and visions for the future

N Bayliss, BVKJ Schmidt - Progress in Polymer Science, 2023 - Elsevier
Hydrophilic polymers are a major class of polymers in polymer science. They are found in
broad range of applications from superabsorbers to drug-delivery. In recent years, a plethora …

Biofilm-Responsive Polymeric Nanoparticles with Self-Adaptive Deep Penetration for In Vivo Photothermal Treatment of Implant Infection

C Wang, W Zhao, B Cao, Z Wang, Q Zhou… - Chemistry of …, 2020 - ACS Publications
Biofilm can protect bacteria from immune attacks and antibiotic inhibition, and bacterial
biofilm hosted in implanted materials and medical devices is a serious threat for modern …

Potentials of nanotechnology in treatment of methicillin-resistant Staphylococcus aureus

Y Gao, Y Chen, Y Cao, A Mo, Q Peng - European journal of medicinal …, 2021 - Elsevier
Abuse of antibiotics has led to the emergence of drug-resistant pathogens. Methicillin-
resistant Staphylococcus aureus (MRSA) was reported just two years after the clinical use of …

Chemical Biology Approach to Reveal the Importance of Precise Subcellular Targeting for Intracellular Staphylococcus aureus Eradication

S Bai, J Song, H Pu, Y Yu, W Song… - Journal of the …, 2023 - ACS Publications
Intracellular bacterial pathogens, such as Staphylococcus aureus, that may hide in
intracellular vacuoles represent the most significant manifestation of bacterial persistence …

Photo‐Enhanced Antimicrobial Activity of Polymers Containing an Embedded Photosensitiser

PR Judzewitsch, N Corrigan, EHH Wong… - Angewandte …, 2021 - Wiley Online Library
This work presents the synthesis of a novel photosensitive acrylate monomer for use as both
a self‐catalyst in the photoinduced electron/energy transfer–reversible addition …

Rational design of self-assembled cationic porphyrin-based nanoparticles for efficient photodynamic inactivation of bacteria

J Li, W Sun, Z Yang, G Gao, HH Ran… - … Applied Materials & …, 2020 - ACS Publications
Bacterial infection has become an urgent health problem in the world. Especially, the
evolving resistance of bacteria to antibiotics makes the issue more challenging, and thus …

Biguanides: Species with versatile therapeutic applications

D Kathuria, AD Raul, P Wanjari, PV Bharatam - European Journal of …, 2021 - Elsevier
Biguanides are compounds in which two guanidine moieties are fused to form a highly
conjugated system. Biguanides are highly basic and hence they are available as salts …

Insights into the polyhexamethylene biguanide (PHMB) mechanism of action on bacterial membrane and DNA: A molecular dynamics study

S Sowlati-Hashjin, P Carbone… - The Journal of Physical …, 2020 - ACS Publications
Polyhexamethylene biguanide (PHMB) is a cationic polymer with antimicrobial and antiviral
properties. It has been commonly accepted that the antimicrobial activity is due to the ability …

High-throughput process for the discovery of antimicrobial polymers and their upscaled production via flow polymerization

PR Judzewitsch, N Corrigan, F Trujillo, J Xu… - …, 2020 - ACS Publications
The combination of high-throughput (HTP) processes and flow-mediated synthesis allows
large data sets to be generated quickly while also permitting large quantities of materials to …