Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Hydrogen sulfide (H 2 S) is now recognized as an endogenous signaling gasotransmitter in
mammals. It is produced by mammalian cells and tissues by various enzymes …

Significance: Hydrogen sulfide (H2S), an important regulator of physiology and health, helps
resolve inflammation and promotes tissue repair in the gastrointestinal tract. Recent …

Metabolic reprogramming powers and polarizes macrophage functions, but the nature and
regulation of this response during infection with pathogens remain controversial. In this …

Airway macrophages (AMs) play key roles in the maintenance of lung immune tolerance.
Tissue tailored, highly specialised and strategically positioned, AMs are critical sentinels of …

Mycobacterium tuberculosis (Mtb) disrupts glycolytic flux in infected myeloid cells through an
unclear mechanism. Flux through the glycolytic pathway in myeloid cells is inextricably …

Hydrogen sulfide (H 2 S) is a toxic, essential gas used in various biological and physical
processes and has been the subject of many targeted studies on its role as a new gas …

Modern lifestyles deviated considerably from the ancestral routines towards major shifts in
diets and increased sedentarism. The trace elements status of the human body is no longer …

Abstract Hypoxia-inducible factor-1 (HIF-1), a heterodimeric transcription factor composed of
the α and β subunits, regulates cellular adaptive responses to hypoxia. Macrophages, which …

Rationale: Our current understanding of tuberculosis (TB) pathophysiology is limited by a
reliance on animal models, the paucity of human TB lung tissue, and traditional …