The water transport system in astrocytes–Aquaporins

Z Zhou, J Zhan, Q Cai, F Xu, R Chai, K Lam, Z Luan… - Cells, 2022 - mdpi.com
Highlights (AQPs) are transmembrane proteins responsible for fast water movement across
cell membranes, including those of astrocytes. The expression and subcellular localization …

[HTML][HTML] Aquaporins: Important players in the cardiovascular pathophysiology

Z Shangzu, X Dingxiong, M ChengJun, C Yan… - Pharmacological …, 2022 - Elsevier
Aquaporin is a membrane channel protein widely expressed in body tissues, which can
control the input and output of water in cells. AQPs are differentially expressed in different …

Canonical bone morphogenetic protein signaling regulates expression of aquaporin-4 and its anchoring complex in mouse astrocytes

N Skauli, E Savchenko, OP Ottersen… - Frontiers in Cellular …, 2022 - frontiersin.org
Aquaporin-4 (AQP4) is the predominant water channel in the brain; it is enriched in
astrocytic foot processes abutting vessels where it is anchored through an interaction with …

[HTML][HTML] Oligodendrocyte dysfunction and regeneration failure: A novel hypothesis of delayed encephalopathy after carbon monoxide poisoning

D Guo, H Hu, S Pan - Medical Hypotheses, 2020 - Elsevier
Carbon monoxide (CO) poisoning usually causes brain lesions and delayed
encephalopathy, also known as delayed neurological sequelae (DNS). Demyelination of …

AQP4 is an Emerging Regulator of Pathological Pain: A Narrative Review

B Zhu, W Zhou, C Chen, A Cao, W Luo… - Cellular and Molecular …, 2023 - Springer
Pathological pain presents significant challenges in clinical practice and research.
Aquaporin-4 (AQP4), which is primarily found in astrocytes, is being considered as a …

Homeostatic status of thyroid hormones and brain water movement as determinant factors in biology of cerebral gliomas: a pilot study using a bioinformatics approach

CB Mendes, LS da Rocha… - Frontiers in …, 2024 - frontiersin.org
Introduction The expression and localization of the water channel transporters, aquaporins
(AQPs), in the brain are substantially modified in gliomas during tumorigenesis, cell …

Klotho gene might antagonize ischemic injury in stroke rats by reducing the expression of AQP4 via P38MAPK pathway

G Zhu, T Xiang, S Liang, K Liu, Z Xiao, Q Ye - Journal of Stroke and …, 2023 - Elsevier
Objectives This study was aimed at exploring whether klotho improved neurologic function
in rats with cerebral infarction by inhibiting P38 mitogen-activated protein kinase (MAPK) …

Sulforaphane Upregulates Cultured Mouse Astrocytic Aquaporin‐4 Expression through p38 MAPK Pathway

C Yang, S Qin, J Zhang, Y Wang… - Journal of Healthcare …, 2022 - Wiley Online Library
Protein misfolding and/or aggregation are common pathological features associated with a
number of neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson …

Ensemble adaptive total variation graph regularized NMF for Singlecell RNA-seq data analysis

YL Zhu, YL Gao, JX Liu, R Zhu… - Current …, 2021 - ingentaconnect.com
Background: Single-cell RNA sequencing techniques have emerged as effective
approaches for finding the heterogeneity between cells and discovering the differentiation …

Therapeutic effect and molecular mechanism of Salvia Miltiorrhiza on rats with acute brain injury after carbon monoxide poisoning based on the strategy of internet …

ZK Li, CH Li, AC Yue, HP Song, XH Liu… - Environmental …, 2022 - Wiley Online Library
The pathogenesis of brain injury caused by carbon monoxide poisoning (COP) is very
complex, and there is no exact and reliable treatment in clinic. In the present study, we …