As the home of cellular genetic information, the nucleus has a critical role in determining cell
fate and function in response to various signals and stimuli. In addition to biochemical …

Cells and tissues can sense and react to the modifications of the physico-chemical
properties of the extracellular environment (ECM) through integrin-based adhesion sites and …

The early development of many organisms involves the folding of cell monolayers, but this
behaviour is difficult to reproduce in vitro; therefore, both mechanistic causes and effects of …

Living cells actively migrate in their environment to perform key biological functions—from
unicellular organisms looking for food to single cells such as fibroblasts, leukocytes or …

Increasing evidence suggests that mechanics play a critical role in regulating brain function
at different scales. Downstream integration of mechanical inputs into biochemical signals …

Single and collective cell migration are fundamental processes critical for physiological
phenomena ranging from embryonic development and immune response to wound healing …

Cells tune adherens junction dynamics to regulate epithelial integrity in diverse (patho)
physiological processes, including cancer metastasis. We hypothesized that the spatially …

Lifeforms are regulated by many physicochemical factors, and these factors could be
controlled to play a role in the construction of artificial living systems. Among these factors …

Cell migration plays important roles in many biological processes, but how migrating cells
orchestrate intracellular molecules and subcellular structures to regulate their speed and …

Skeletal muscle fibers are formed by the fusion of mononucleated myoblasts into long linear
myotubes, which differentiate and reorganize into multinucleated myofibers that assemble in …