Embryo–epithelium interactions during implantation at a glance

JD Aplin, PT Ruane - Journal of cell science, 2017 - journals.biologists.com
At implantation, with the acquisition of a receptive phenotype in the uterine epithelium, an
initial tenuous attachment of embryonic trophectoderm initiates reorganisation of epithelial …

Three-dimensional culture models of human endometrium for studying trophoblast-endometrium interaction during implantation

X Li, SP Kodithuwakku, RWS Chan… - Reproductive Biology …, 2022 - Springer
During implantation, a symphony of interaction between the trophoblast originated from the
trophectoderm of the implanting blastocyst and the endometrium leads to a successful …

The role of the osteopontin–integrin αvβ3 interaction at implantation: functional analysis using three different in vitro models

YJ Kang, K Forbes, J Carver, JD Aplin - Human Reproduction, 2014 - academic.oup.com
STUDY QUESTION Does the interaction between integrin and its ligand osteopontin (OPN)
mediate embryonic attachment to endometrial epithelium at implantation? SUMMARY …

Transcriptome profiling analysis of uterus during chicken laying periods

T Sun, C Xiao, Z Yang, J Deng, X Yang - BMC genomics, 2023 - Springer
The avian eggshell is formed in the uterus. Changes in uterine function may have a
significant effect on eggshell quality. To identify the vital genes impacting uterine functional …

Hormonal fluctuations during the estrous cycle modulate heme oxygenase-1 expression in the uterus

ML Zenclussen, PA Casalis, F Jensen… - Frontiers in …, 2014 - frontiersin.org
Deletion of the heme oxygenase-1 (HO-1)(Hmox1) locus in mice results in intrauterine
lethality. The expression of the heme catabolizing enzyme encoded by this gene, namely …

Uterine receptivity and embryo–uterine interactions in embryo implantation: lessons from mice

M Egashira, Y Hirota - Reproductive Medicine and Biology, 2013 - Springer
Implantation is a process of the first feto-maternal encounter in the uterus. A competent
blastocyst and a receptive uterus are critical for successful implantation. For an acquisition of …

Differential regulation of osteopontin and CD44 correlates with infertility status in PCOS patients

R Paravati, N De Mello, EK Onyido, LW Francis… - Journal of Molecular …, 2020 - Springer
Endometrial receptivity is mediated by adhesion molecules at the endometrium-trophoblast
interface where osteopontin (OPN) and CD44 form a protein complex that plays an important …

Characterisation of osteopontin in an in vitro model of embryo implantation

SC Berneau, PT Ruane, DR Brison, SJ Kimber… - Cells, 2019 - mdpi.com
At the onset of pregnancy, embryo implantation is initiated by interactions between the
endometrial epithelium and the outer trophectoderm cells of the blastocyst. Osteopontin …

Endometrial Intracrinology—generation of an estrogen-dominated microenvironment in the secretory phase of women

DA Gibson, KJ McInnes, HOD Critchley… - The Journal of …, 2013 - academic.oup.com
Context: The human endometrium is a complex multicellular tissue subject to cyclical
fluctuations in ovarian-derived steroid hormones. Fertile cycles are characterized by …

SPP1 expression in the mouse uterus and placenta: implications for implantation

AC Kramer, DW Erikson, BA McLendon… - Biology of …, 2021 - academic.oup.com
Abstract Secreted phosphoprotein 1 (SPP1, also known as osteopontin) binds integrins to
mediate cell–cell and cell–extracellular matrix communication to promote cell adhesion …