Lipid monolayer collapse and microbubble stability

JJ Kwan, MA Borden - Advances in colloid and interface science, 2012 - Elsevier
Microbubbles are micrometer-size gaseous particles suspended in water, and they are often
stabilized by a lipid monolayer shell. Natural microbubbles are found in freshwater and …

A review of phospholipid encapsulated ultrasound contrast agent microbubble physics

B Helfield - Ultrasound in medicine & biology, 2019 - Elsevier
Ultrasound contrast agent microbubbles have expanded the utility of biomedical ultrasound
from anatomic imaging to the assessment of microvascular blood flow characteristics and …

Biophysical insight into mechanisms of sonoporation

B Helfield, X Chen, SC Watkins… - Proceedings of the …, 2016 - National Acad Sciences
This study presents a unique approach to understanding the biophysical mechanisms of
ultrasound-triggered cell membrane disruption (ie, sonoporation). We report direct …

Toward precisely controllable acoustic response of shell-stabilized nanobubbles: High yield and narrow dispersity

A Jafari Sojahrood, AC de Leon, R Lee, M Cooley… - ACS …, 2021 - ACS Publications
Understanding the pressure dependence of the nonlinear behavior of ultrasonically excited
phospholipid-stabilized nanobubbles (NBs) is important for optimizing ultrasound exposure …

Probing the pressure dependence of sound speed and attenuation in bubbly media: Experimental observations, a theoretical model and numerical calculations

AJ Sojahrood, Q Li, H Haghi, R Karshafian… - Ultrasonics …, 2023 - Elsevier
The problem of attenuation and sound speed of bubbly media has remained partially
unsolved. Comprehensive data regarding pressure-dependent changes of the attenuation …

Nonlinear dynamics of acoustic bubbles excited by their pressure-dependent subharmonic resonance frequency: influence of the pressure amplitude, frequency …

AJ Sojahrood, R Earl, H Haghi, Q Li, TM Porter… - Nonlinear …, 2021 - Springer
Nonlinear behavior of bubbles, and most importantly 1 2 1 2-order subharmonics (SH), are
used to increase the contrast-to-tissue ratio (CTR) in diagnostic ultrasound (US) and to …

[HTML][HTML] Opening of endothelial cell–cell contacts due to sonoporation

I Beekers, M Vegter, KR Lattwein, F Mastik… - Journal of controlled …, 2020 - Elsevier
Ultrasound insonification of microbubbles can locally increase vascular permeability to
enhance drug delivery. To control and optimize the therapeutic potential, we need to better …

Viability of endothelial cells after ultrasound-mediated sonoporation: Influence of targeting, oscillation, and displacement of microbubbles

T van Rooij, I Skachkov, I Beekers, KR Lattwein… - Journal of Controlled …, 2016 - Elsevier
Microbubbles (MBs) have been shown to create transient or lethal pores in cell membranes
under the influence of ultrasound, known as ultrasound-mediated sonoporation. Several …

Functionalized multiwalled carbon nanotubes as ultrasound contrast agents

LG Delogu, G Vidili, E Venturelli… - Proceedings of the …, 2012 - National Acad Sciences
Ultrasonography is a fundamental diagnostic imaging tool in everyday clinical practice.
Here, we are unique in describing the use of functionalized multiwalled carbon nanotubes …

[HTML][HTML] Nonlinear dynamics and bifurcation structure of ultrasonically excited lipid coated microbubbles

AJ Sojahrood, H Haghi, R Karshafian… - Ultrasonics Sonochemistry, 2021 - Elsevier
In many applications, microbubbles (MBs) are encapsulated by a lipid coating to increase
their stability. However, the complex behavior of the lipid coating including buckling and …