Obesity and the risk of cardiometabolic diseases

PL Valenzuela, P Carrera-Bastos… - Nature reviews …, 2023 - nature.com
The prevalence of obesity has reached pandemic proportions, and now approximately 25%
of adults in Westernized countries have obesity. Recognized as a major health concern …

The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions

TJ Littlejohns, J Holliday, LM Gibson, S Garratt… - Nature …, 2020 - nature.com
UK Biobank is a population-based cohort of half a million participants aged 40–69 years
recruited between 2006 and 2010. In 2014, UK Biobank started the world's largest multi …

Visceral and ectopic fat, atherosclerosis, and cardiometabolic disease: a position statement

IJ Neeland, R Ross, JP Després… - The lancet Diabetes & …, 2019 - thelancet.com
Findings from epidemiological studies over the past 30 years have shown that visceral
adipose tissue, accurately measured by CT or MRI, is an independent risk marker of …

Causes, consequences, and treatment of metabolically unhealthy fat distribution

N Stefan - The lancet Diabetes & endocrinology, 2020 - thelancet.com
An increase in fat mass is considered to be an important risk factor for the worldwide
increase in type 2 diabetes and cardiovascular disease. However, for a given fat mass, there …

BMI-adjusted adipose tissue volumes exhibit depot-specific and divergent associations with cardiometabolic diseases

S Agrawal, MDR Klarqvist, N Diamant… - Nature …, 2023 - nature.com
For any given body mass index (BMI), individuals vary substantially in fat distribution, and
this variation may have important implications for cardiometabolic risk. Here, we study …

[HTML][HTML] Exome-wide association study on alanine aminotransferase identifies sequence variants in the GPAM and APOE associated with fatty liver disease

O Jamialahmadi, RM Mancina, E Ciociola… - Gastroenterology, 2021 - Elsevier
Background & Aims Fatty liver disease (FLD) is a growing epidemic that is expected to be
the leading cause of end-stage liver disease within the next decade. Both environmental …

Reference values for skeletal muscle mass–current concepts and methodological considerations

CO Walowski, W Braun, MJ Maisch, B Jensen, S Peine… - Nutrients, 2020 - mdpi.com
Assessment of a low skeletal muscle mass (SM) is important for diagnosis of ageing and
disease-associated sarcopenia and is hindered by heterogeneous methods and …

Nascent to novel methods to evaluate malnutrition and frailty in the surgical patient

CM Prado, KL Ford, MC Gonzalez… - Journal of Parenteral …, 2023 - Wiley Online Library
Preoperative nutrition status is an important determinant of surgical outcomes, yet
malnutrition assessment is not integrated into all surgical pathways. Given its importance …

A systematic review of automated segmentation of 3D computed‐tomography scans for volumetric body composition analysis

DVC Mai, I Drami, ET Pring, LE Gould… - Journal of Cachexia …, 2023 - Wiley Online Library
Automated computed tomography (CT) scan segmentation (labelling of pixels according to
tissue type) is now possible. This technique is being adapted to achieve three‐dimensional …

Liver, visceral and subcutaneous fat in men and women of South Asian and white European descent: a systematic review and meta-analysis of new and published …

S Iliodromiti, J McLaren, N Ghouri, MR Miller… - Diabetologia, 2023 - Springer
Abstract Aims/hypothesis South Asians have a two-to fivefold higher risk of developing type
2 diabetes than those of white European descent. Greater central adiposity and storage of …