[HTML][HTML] Changes in the mammary gland during aging and its links with breast diseases: aged mammary gland and breast diseases

J Lin, S Ye, H Ke, L Lin, X Wu, M Guo… - Acta biochimica et …, 2023 - ncbi.nlm.nih.gov
The functional capacity of organisms declines in the process of aging. In the case of breast
tissue, abnormal mammary gland development can lead to dysfunction in milk secretion, a …

Estrogen signaling as a bridge between the nucleus and mitochondria in cardiovascular diseases

E Guajardo-Correa, JF Silva-Agüero, X Calle… - Frontiers in Cell and …, 2022 - frontiersin.org
Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide.
Epidemiological studies indicate that pre-menopausal women are more protected against …

SIRT3 Negatively Regulates TFH-Cell Differentiation in Cancer

Y Hou, Y Cao, Y He, L Dong, L Zhao, Y Dong… - Cancer Immunology …, 2024 - AACR
Follicular helper T (TFH) cells are essential for inducing germinal center (GC) reactions to
mediate humoral adaptive immunity in tumors; however, the mechanisms underlying TFH …

Polydatin and Nicotinamide Rescue the Cellular Phenotype of Mitochondrial Diseases by Mitochondrial Unfolded Protein Response (mtUPR) Activation

P Cilleros-Holgado, D Gómez-Fernández… - Biomolecules, 2024 - mdpi.com
Primary mitochondrial diseases result from mutations in nuclear DNA (nDNA) or
mitochondrial DNA (mtDNA) genes, encoding proteins crucial for mitochondrial structure or …

Is SIRT3 and Mitochondria a Reliable Target for Parkinson's Disease and Aging? A Narrative Review

AT Kandy, J Chand, MZ Baba, G Subramanian - Molecular Neurobiology, 2024 - Springer
Aging is a complicated degenerative process that has been thoroughly researched in a
variety of taxa, including mammals, worms, yeast, and flies. One important controller of …