Bioinformatics analysis of whole exome sequencing data

PJ Ulintz, W Wu, CM Gates - Chronic Lymphocytic Leukemia: Methods and …, 2019 - Springer
This chapter contains a step-by-step protocol for identifying somatic SNPs and small Indels
from next-generation sequencing data of tumor samples and matching normal samples. The …

Gapim: Discovering genetic variations on a real processing-in-memory system

N Abecassis, J Gómez-Luna, O Mutlu, R Ginosar… - bioRxiv, 2023 - biorxiv.org
Variant calling is a fundamental stage in genome analysis that identifies mutations
(variations) in a sequenced genome relative to a known reference genome. Pair-HMM is a …

Rare And Undiagnosed Liver Diseases: New Insights From Genomic And Single Cell Transcriptomic Analyses

C Konkwo - 2024 - elischolar.library.yale.edu
Chronic liver disease (CLD) is a major global health problem, leading to an estimatedtwo
million annual deaths worldwide. Advances in next generation sequencing (NGS) …

Pair-HMM accelerator based on non-cooperative structure

P Wang, Y Lei, Y Dou - IEICE Electronics Express, 2019 - jstage.jst.go.jp
Abstract Pair Hidden Markov Model (Pair-HMM) forward algorithm is gaining increasing
popularity in biological research tools. We propose a novel non-cooperative structure of Pair …