The review summarizes the abundant information on the 35 identified peptidoglycan (PG)
hydrolases of Escherichia coli classified into 12 distinct families, including mainly …

The peptidoglycan (PG) cell wall is a unique macromolecule responsible for both shape
determination and cellular integrity under osmotic stress in virtually all bacteria. A …

The first gene of a family of prokaryotic proteases with a specificity for L, D-configured
peptide bonds has been identified in Escherichia coli. The gene named ldcA encodes a …

The bacterial cell wall is made of peptidoglycan (PG), a polymer that is essential for the
maintenance of cell shape and survival. During growth, bacteria remodel their PG, releasing …

Bacterial peptidoglycan amidases are a large and diverse group of enzymes. During the last
few years, genomic sequence information has accumulated to an extent such that lists of …

The peptidoglycan (PG) cell wall constitutes the main defense barrier of bacteria against
environmental insults and acts as communication interface. The biochemistry of this …

ld-Carboxypeptidases (EC 3.4. 17.13) are named for their ability to cleave amide bonds
between l-and d-amino acids, which occur naturally in bacterial peptidoglycan. They are …

During evolution, enzymes can undergo shifts in preferred substrates or in catalytic activities.
An intriguing question is how enzyme function changes following horizontal gene transfer …

The heptapeptide-nucleotide microcin C (McC) is a potent inhibitor of enteric bacteria
growth. Inside a sensitive cell, McC is processed by aminopeptidases, which release a …

Approximately 50% of cell wall peptidoglycan in Gram-negative bacteria is recycled with
each generation. The primary substrates used for peptidoglycan biosynthesis and recycling …