[HTML][HTML] Novel wine in an old bottle: Preventive and therapeutic potentials of andrographolide in atherosclerotic cardiovascular diseases

T Gou, M Hu, M Xu, Y Chen, R Chen, T Zhou… - Journal of …, 2023 - Elsevier
Atherosclerotic cardiovascular disease (ASCVD) frequently results in sudden death and
poses a serious threat to public health worldwide. The drugs approved for the prevention …

[HTML][HTML] Empagliflozin suppressed cardiac fibrogenesis through sodium-hydrogen exchanger inhibition and modulation of the calcium homeostasis

CC Chung, YK Lin, YC Chen, YH Kao, YH Yeh… - Cardiovascular …, 2023 - Springer
Background The novel sodium-glucose co-transporter 2 inhibitor (SGLT2i) potentially
ameliorates heart failure and reduces cardiac arrhythmia. Cardiac fibrosis plays a pivotal …

[HTML][HTML] Metabolomics analysis delineates the therapeutic effects of hydroethanolic extract of Cucumis sativus L. seeds on hypertension and isoproterenol-induced …

M Wahid, F Saqib, L Chicea, HT Ahmedah… - Biomedicine & …, 2022 - Elsevier
Cucumis sativus L., widely cultivated as an edible vegetable. Its seeds are well reputed for
cardiovascular preventive properties. However, the mechanisms underlying for …

Scientific basis for medicinal use of Citrullus lanatus (Thunb.) in diarrhea and asthma: In vitro, in vivo and in silico studies

M Wahid, F Saqib - Phytomedicine, 2022 - Elsevier
Abstract Background Citrullus lanatus (Thunb.) is a member of the Cucurbitaceae family,
commonly farmed as an edible vegetable around the globe. It has been used in traditional …

PLGA nanoparticles enhanced cardio-protection of scutellarin and paeoniflorin against isoproterenol-induced myocardial ischemia in rats

C Yang, S Yang, S Fang, L Li, J Jing, W Liu… - International Journal of …, 2023 - Elsevier
This study aims to examine the impact of the microfluidic preparation process on the quality
of poly (lactic-co-glycolic acid)(PLGA) nanoparticles (NPs) co-delivered with scutellarin …

[HTML][HTML] Dynamic Changes in Ion Channels during Myocardial Infarction and Therapeutic Challenges

T Song, W Hui, M Huang, Y Guo, M Yu, X Yang… - International Journal of …, 2024 - mdpi.com
In different areas of the heart, action potential waveforms differ due to differences in the
expressions of sodium, calcium, and potassium channels. One of the characteristics of …

[HTML][HTML] Metabolomics based mechanistic insights to vasorelaxant and cardioprotective effect of ethanolic extract of Citrullus lanatus (Thunb.) Matsum. & Nakai. seeds …

F Saqib, M Wahid, AA Al-Huqail, HT Ahmedah, N Bigiu… - Phytomedicine, 2022 - Elsevier
Abstract Background Cardiovascular diseases (CVDs) are a significant cause of morbidity
and death in the current world, posing a challenge to both developing and industrialized …

[HTML][HTML] Cucumis sativus L. Seeds Ameliorate Muscular Spasm-Induced Gastrointestinal and Respiratory Disorders by Simultaneously Inhibiting Calcium Mediated …

M Wahid, F Saqib, HT Ahmedah, CM Gavris, V De Feo… - Pharmaceuticals, 2021 - mdpi.com
Cucumis sativus L. is globally cultivated as an edible vegetable. Besides its nutritional
benefits, it is used in traditional medicines against various ailments. The current study was …

Andrographolide protects against atrial fibrillation by alleviating oxidative stress injury and promoting impaired mitochondrial bioenergetics

P Yu, J Cao, H Sun, Y Gong, H Ying, X Zhou… - Journal of Zhejiang …, 2023 - Springer
Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia seen in clinical settings, which
has been associated with substantial rates of mortality and morbidity. However, clinically …

Fumaria indica (Hausskn.) Pugsley Hydromethanolic Extract: Bioactive Compounds Identification, Hypotensive Mechanism, and Cardioprotective Potential …

SAH Shah, SL Rana, M Mohany, M Milošević… - ACS …, 2024 - ACS Publications
Fumaria indica (Hausskn.) Pugsley (FIP), a member of the Papaveraceae family, has a
documented history of use in traditional medicine to treat cardiovascular ailments …