Objective To explore and evaluate the most common factors causing therapeutic non-
compliance. Methods A qualitative review was undertaken by a literature search of the …

Patients with gastro-oesophageal reflux disease (GORD) who are not responding to proton
pump inhibitors (PPIs) given once daily are very common. Various underlying mechanisms …

Electrical stimulation is a promising method to modulate gastrointestinal disorders. However,
conventional stimulators need invasive implantation and removal surgeries associated with …

Proton‐pump inhibitor failure has become a common clinical dilemma in gastrointestinal
clinics and has been increasingly encountered at the primary care level as well. Underlying …

Proton pump inhibitors (PPIs)[omeprazole, lansoprazole, pantoprazole, rabeprazole and
esomeprazole] are widely utilised for the treatment of gastro-oesophageal reflux disease, as …

Abstract Background and Aims: Since the publication of the Asia‐Pacific GERD consensus
in 2004, more data concerning the epidemiology and management of gastroesophageal …

More than 15 years after the launch of omeprazole in 1988, proton‐pump inhibitors remain
central to the management of acid‐suppression disorders and are unchallenged with regard …

Proton pump inhibitors (PPIs) are superior to histamine-2 receptor antagonists for the
treatment of gastroesophageal reflux disease (GERD) and erosive esophagitis …

A significant percentage of patients with gastroesophageal reflux disease (GERD) will not
respond to proton pump inhibitor (PPI) therapy. The causes of PPI-refractory GERD are …

Gastroesophageal reflux disease (GERD) is one of the most frequent gastrointestinal
disorders. Proton pump inhibitors (PPIs) are effective in healing lesions and improving …