Breast cancer cells frequently express tumor-associated antigens that can elicit immune
responses to eradicate cancer. Cancer-testis antigens (CTAs) are a group of tumor …

Breast cancer is the most common cancer diagnosed and is the second leading cause of
cancer death among women in the US. For breast cancer, early diagnosis and efficient …

CD47 is a signaling receptor for thrombospondin-1 and the counter-receptor for signal-
regulatory protein-α (SIRPα). By inducing inhibitory SIRPα signaling, elevated CD47 …

Overexpression of HER2 has been reported in around 25% of human breast cancers.
Despite recent advances in HER2 targeted therapy, many patients still experience primary …

The identification of colorectal cancer (CRC) molecular targets is needed for the
development of drugs that improve patient survival. We investigated the functional role of …

A range of antitumor agents for cancer treatment is available; however, they show low
specificity, which often limit their use. Recently, we have reported the preparation of folate …

Overexpression of TRIP13, a member of the AAA‐ATPase family, is linked with various
cancers, but its role in metastasis is unknown in colorectal cancer (CRC). In the current …

Deposition, remodeling, and signaling of the extracellular matrix facilitate tumor growth and
metastasis. Here, we demonstrated that an enzyme, collagen prolyl 4-hydroxylase, alpha …

Breast cancer ranks as the leading cause of death in lethal malignancies among women
worldwide, with a sharp increase of incidence since 2008. Triple negative breast cancer …

Background The chemotherapy-resistance of triple-negative breast cancer (TNBC) remains
a major challenge. The Nek2B kinase and β-catenin serve as crucial regulators of mitotic …