Cancer vaccines: Building a bridge over troubled waters
MLC Sellars, CJ Wu, EF Fritsch - Cell, 2022 - cell.com
Cancer vaccines aim to direct the immune system to eradicate cancer cells. Here we review
the essential immunologic concepts underpinning natural immunity and highlight the …
the essential immunologic concepts underpinning natural immunity and highlight the …
Rethinking antigen source: cancer vaccines based on whole tumor cell/tissue lysate or whole tumor cell
L Diao, M Liu - Advanced Science, 2023 - Wiley Online Library
Cancer immunotherapies have improved human health, and one among the important
technologies for cancer immunotherapy is cancer vaccine. Antigens are the most important …
technologies for cancer immunotherapy is cancer vaccine. Antigens are the most important …
Engineered stem cells by emerging biomedical stratagems
Stem cell therapy holds immense potential as a viable treatment for a widespread range of
intractable disorders. As the safety of stem cell transplantation having been demonstrated in …
intractable disorders. As the safety of stem cell transplantation having been demonstrated in …
Antitumor activities of interleukin-12 in melanoma
W Gao, J Pan, J Pan - Cancers, 2022 - mdpi.com
Simple Summary Immunotherapy has been evolving rapidly in recent years. As a key
component of the immune system, cytokines play essential roles not only in immune …
component of the immune system, cytokines play essential roles not only in immune …
Advances and clinical applications of immune checkpoint inhibitors in hematological malignancies
W Sun, S Hu, X Wang - Cancer Communications, 2024 - Wiley Online Library
Immune checkpoints are differentially expressed on various immune cells to regulate
immune responses in tumor microenvironment. Tumor cells can activate the immune …
immune responses in tumor microenvironment. Tumor cells can activate the immune …
Intratumoral administration of unconjugated Accum™ impairs the growth of pre‐established solid lymphoma tumors
JP Bikorimana, N El‐Hachem, M Moreau… - Cancer …, 2023 - Wiley Online Library
The Accum™ technology was initially designed to enhance the bioaccumulation of a given
molecule in target cells. It does so by triggering endosomal membrane damages allowing …
molecule in target cells. It does so by triggering endosomal membrane damages allowing …
An engineered Accum‐E7 protein‐based vaccine with dual anti‐cervical cancer activity
JP Bikorimana, J Abusarah, M Gonçalves… - Cancer …, 2024 - Wiley Online Library
Worldwide prevalence of cervical cancer decreased significantly with the use of human
papilloma virus (HPV)‐targeted prophylactic vaccines. However, these multivalent antiviral …
papilloma virus (HPV)‐targeted prophylactic vaccines. However, these multivalent antiviral …
LSD1 inhibition enhances the immunogenicity of mesenchymal stromal cells by eliciting a dsRNA stress response
F Mardani, W Saad, N El-Hachem, JP Bikorimana… - Cells, 2022 - mdpi.com
Mesenchymal stromal cells (MSCs) are commonly known for their immune-suppressive
abilities. However, our group provided evidence that it is possible to convert MSCs into …
abilities. However, our group provided evidence that it is possible to convert MSCs into …
The Dark Side of Adipose-Derived Mesenchymal Stromal Cells in Cutaneous Oncology: Roles, Expectations, and Potential Pitfalls
A Paganelli, E Rossi, C Magnoni - Stem Cells and Development, 2022 - liebertpub.com
Adipose-derived stromal cells (ADSCs) have well-established regenerative and
immunomodulatory properties. For such reasons, ADSCs are currently under investigation …
immunomodulatory properties. For such reasons, ADSCs are currently under investigation …
[HTML][HTML] A new era of gene and cell therapy for cancer: A narrative review
L Wang, G Liu, L Zheng, H Long… - Annals of Translational …, 2023 - ncbi.nlm.nih.gov
A new era of gene and cell therapy for cancer: a narrative review - PMC Back to Top Skip to
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main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main …