Interleukin-1 (IL-1) is the prototypical inflammatory cytokine: two distinct ligands (IL-1α and IL-
1β) bind the IL-1 type 1 receptor (IL-1R1) and induce a myriad of secondary inflammatory …

Background Epilepsy is a common and debilitating consequence of traumatic brain injury
(TBI). Seizures contribute to progressive neurodegeneration and poor functional and …

Status epilepticus (SE) is one of the most serious manifestations of epilepsy. Systemic
inflammation and damage of blood-brain barrier (BBB) are etiologic cofactors in the …

Aim. To review the literature about febrile seizures and GEFS plus with special emphasis on
management and outcome. Methods. Selected literature review. Results. Febrile seizures …

The role of viral infection in the etiology of febrile seizures is a relatively neglected field of
neurologic research. A National Institutes of Health Consensus Conference (1981) omitted …

Complex neurodevelopmental disorders, such as schizophrenia, autism, attention deficit
(hyperactivity) disorder,(manic) depressive illness and addiction, are thought to result from …

Febrile seizures (FSs) occur in children older than 1 month and without prior afebrile
seizures in the absence of a central nervous system infection or acute electrolyte imbalance …

Febrile seizures (FS) represent the most common form of childhood seizures. They affect 2–
5% of infants in the Caucasian population and are even more common in the Japanese …

During acute neuroinflammation, increased levels of cytokines within the brain may
contribute to synaptic reorganization that results in long-term changes in network …

Interleukin-1 (IL-1) has a multitude of functions in the central nervous system. Some of them
involve mechanisms that are related to epileptogenesis. The role of IL-1 in seizures and …