Amide bond construction has garnered significant interest in recent decades due to amides
being one of the most prevalent functional groups among bioactive molecules. Out of the …

The first enantioselective synthesis of α‐allenylic amides and ketones through allenylic
alkylation of vinyl azides is reported. In these chemodivergent reactions, cooperatively …

A highly chemo-and enantioselective alkylation of vinyl azides with 3-bromo-3-substituted
oxindoles was achieved through a chiral N, N′-dioxide/Ni (OTf) 2-mediated conjugate …

Among the unstabilized enolates used as nucleophiles in iridium-catalyzed asymmetric
allylic alkylation reactions, amide enolates are the least explored. Vinyl azides are now …

A catalytic asymmetric conjugate addition/Schmidt-type rearrangement of vinyl azides and
(E)-alkenyloxindoles was realized. It afforded a variety of optically active 3, 2′-pyrrolinyl …

The development of a transition-metal-catalyzed [3+ 2] cycloaddition for one-pot synthesis of
2-substituted benzofurans from vinyl azides and benzoquinone is reported. This reaction …

An enantioselective [4+ 2] cycloaddition reaction of α-fluorostyrenes with N-benzoyl imines
was demonstrated using a chiral phosphoric acid catalyst. Cycloaddition products having …

Chiral acid organocatalysts including hydrogen bond catalysts and chiral Brønsted acids
surged after 2000. Recent progress in the chiral Brønsted acid catalysis mainly after 2010 is …

Enantioselective allenylic alkylation reactions of unstabilized enolates have never been
reported. We now present a unified fragment-coupling strategy for the first enantioselective …

Among the unstabilized enolates used as nucleophile in iridium-catalyzed asymmetric allylic
alkylation reactions, amide enolates are least explored. Vinyl azides are now employed as …