[PDF][PDF] Paradoxical impact of cholesterol on lipid packing and cell stiffness

MA Ayee, I Levitan - Front Biosci (Landmark Ed), 2016 - article.imrpress.com
Cell stiffness or deformability is a fundamental property that is expected to play a major role
in multiple cellular functions. It is well known that cell stiffness is dominated by the …

Remote Co-loading of amphipathic acid drugs in neutrophil nanovesicles infilled with cholesterol mitigates lung bacterial infection and inflammation

J Gao, Y Su, Z Wang - Biomaterials, 2023 - Elsevier
Lung bacterial infections could result in acute lung inflammation/injury (ALI) that propagates
to its severe form, acute respiratory distress syndrome (ADRS) leading to the death. The …

The evolution of cholesterol-rich membrane in oxygen adaption: the respiratory system as a model

JP Zuniga-Hertz, HH Patel - Frontiers in Physiology, 2019 - frontiersin.org
The increase in atmospheric oxygen levels imposed significant environmental pressure on
primitive organisms concerning intracellular oxygen concentration management. Evidence …

Membrane cholesterol and substrate stiffness co-ordinate to induce the remodelling of the cytoskeleton and the alteration in the biomechanics of vascular smooth …

HJ Sanyour, N Li, AP Rickel, JD Childs… - Cardiovascular …, 2019 - academic.oup.com
Aims Cholesterol not only deposits in foam cells at the atherosclerotic plaque, but also plays
an important role as a regulator of cell migration in atherogenesis. In addition, the …

Statin‐mediated cholesterol depletion exerts coordinated effects on the alterations in rat vascular smooth muscle cell biomechanics and migration

HJ Sanyour, N Li, AP Rickel, HM Torres… - The Journal of …, 2020 - Wiley Online Library
Key points This study demonstrates and evaluates the changes in rat vascular smooth
muscle cell biomechanics following statin‐mediated cholesterol depletion. Evidence is …

Vasoactive agonists exert dynamic and coordinated effects on vascular smooth muscle cell elasticity, cytoskeletal remodelling and adhesion

Z Hong, Z Sun, M Li, Z Li, F Bunyak… - The Journal of …, 2014 - Wiley Online Library
Key points This study demonstrates rapid and dynamic changes in adhesion and cell
elasticity following agonist stimulation that culminate in a remodelled cytoskeleton in …

Subtle regulation of scaffold stiffness for the optimized control of cell behavior

X Lu, Z Ding, F Xu, Q Lu, DL Kaplan - ACS Applied Bio Materials, 2019 - ACS Publications
The rigidity of extracellular matrices can impact cell fate, guide tissue development, and
initiate tumor formation. Scaffolds such as hydrogels with tunable levels of stiffness have …

The interplay of membrane cholesterol and substrate on vascular smooth muscle biomechanics

HJ Sanyour, AP Rickel, Z Hong - Current topics in membranes, 2020 - Elsevier
Cardiovascular disease (CVD) remains the primary cause of death worldwide. Specifically,
atherosclerosis is a CVD characterized as a slow progressing chronic inflammatory disease …

The interplay of membrane cholesterol and substrate on vascular smooth muscle biomechanics. pdf

HJ Hong, N Li, AP Rickel, JD Childs, CN Kinser - 2024 - hra.figshare.com
Cholesterol is implicated not only in the formation of foam cells within atherosclerotic
plaques but also in regulating cell migration during atherogenesis. As atherosclerosis …

Modulation of intraocular pressure by tuning transcriptional control of lipid synthesis

T Wang - 2024 - search.proquest.com
Glaucoma is an age-related optic neuropathy and is one of the leading causes of
irreversible blindness. Primary open-angle glaucoma (POAG) is the predominant subtype of …