Candida auris Genetics and Emergence
A Chowdhary, K Jain, N Chauhan - Annual Review of …, 2023 - annualreviews.org
Candida auris is a multidrug-resistant fungal pathogen that presents a serious threat to
global human health. Since the first reported case in 2009 in Japan, C. auris infections have …
global human health. Since the first reported case in 2009 in Japan, C. auris infections have …
Drug resistance and tolerance in fungi
J Berman, DJ Krysan - Nature Reviews Microbiology, 2020 - nature.com
Systemic fungal infections pose a serious clinical problem. Treatment options are limited,
and antifungal drug resistance is increasing. In addition, a substantial proportion of patients …
and antifungal drug resistance is increasing. In addition, a substantial proportion of patients …
Breakthrough invasive fungal infections: Who is at risk?
The epidemiology of invasive fungal infections (IFIs) in immunocompromised individuals has
changed over the last few decades, partially due to the increased use of antifungal agents to …
changed over the last few decades, partially due to the increased use of antifungal agents to …
Fungal cell wall: emerging antifungals and drug resistance
SL Lima, AL Colombo… - Frontiers in microbiology, 2019 - frontiersin.org
The cell wall is an essential component in fungal homeostasis. The lack of a covering wall in
human cells makes this component an attractive target for antifungal development. The host …
human cells makes this component an attractive target for antifungal development. The host …
Candida albicans Antifungal Resistance and Tolerance in Bloodstream Infections: The Triad Yeast-Host-Antifungal
S Costa-de-Oliveira, AG Rodrigues - Microorganisms, 2020 - mdpi.com
Candida albicans represents the most frequent isolated yeast from bloodstream infections.
Despite the remarkable progress in diagnostic and therapeutic approaches, these infections …
Despite the remarkable progress in diagnostic and therapeutic approaches, these infections …
Defining breakthrough invasive fungal infection–Position paper of the mycoses study group education and research consortium and the European Confederation of …
Breakthrough invasive fungal infections (IFI s) have emerged as a significant problem in
patients receiving systemic antifungals; however, consensus criteria for defining …
patients receiving systemic antifungals; however, consensus criteria for defining …
[HTML][HTML] Drug resistance and novel therapeutic approaches in invasive candidiasis
SE Murphy, T Bicanic - Frontiers in cellular and infection microbiology, 2021 - frontiersin.org
Candida species are the leading cause of invasive fungal infections worldwide and are
associated with acute mortality rates of~ 50%. Mortality rates are further augmented in the …
associated with acute mortality rates of~ 50%. Mortality rates are further augmented in the …
A comprehensive overview of the medicinal chemistry of antifungal drugs: perspectives and promise
The emergence of new fungal pathogens makes the development of new antifungal drugs a
medical imperative that in recent years motivates the talents of numerous investigators …
medical imperative that in recent years motivates the talents of numerous investigators …
[HTML][HTML] Facilitators of adaptation and antifungal resistance mechanisms in clinically relevant fungi
MWJ Hokken, BJ Zwaan, WJG Melchers… - Fungal genetics and …, 2019 - Elsevier
Opportunistic fungal pathogens can cause a diverse range of diseases in humans. The
increasing rate of fungal infections caused by strains that are resistant to commonly used …
increasing rate of fungal infections caused by strains that are resistant to commonly used …
Candida parapsilosis sensu stricto Antifungal Resistance Mechanisms and Associated Epidemiology
I Franconi, C Rizzato, N Poma, A Tavanti, A Lupetti - Journal of Fungi, 2023 - mdpi.com
Fungal diseases cause millions of deaths per year worldwide. Antifungal resistance has
become a matter of great concern in public health. In recent years rates of non-albicans …
become a matter of great concern in public health. In recent years rates of non-albicans …