Dendritic cells (DCs) are antigen-presenting cells with a unique ability to induce primary
immune responses. DCs capture and transfer information from the outside world to the cells …

It is now possible to grow DC-like cells in culture17-21 and extensive cell membrane
processes that are acquired late the first monoclonal antibodies (MoAbs) 22, 23 that react …

Essential to the dendritic cell system of antigen-presenting cells are the veiled dendritic cells
that traverse afferent lymph to enter lymph nodes, where they initiate immune responses …

Substantial numbers of dendritic cells (DCs) are found in the T‐cell areas of peripheral
lymphoid organs such as the spleen, lymph node and Peyer's patch. By electron microscopy …

We have investigated an improved method for generating sizable numbers of mature
dendritic cells from nonproliferating progenitors in human blood. The procedure uses 1 …

Dendritic Cell (DC)-based vaccination approaches in man require a reproducible DC
generation method that can be performed in conformity with GMP (Good Manufacturing …

We have identified a novel lysosome-associated membrane glycoprotein localized on
chromosome 3q26. 3-q27, DC-LAMP, which is homologous to CD68. DC-LAMP mRNA is …

The fascins are a structurally unique and evolutionarily conserved group of actin cross‐
linking proteins. Fascins function in the organisation of two major forms of actin‐based …

Publisher Summary This chapter provides an overview of dendritic cells (DCs). Dendritic
cells were first identified in the epidermis and were termed “Langerhans cells.” DCs are now …

Fascins are actin‐binding proteins that cross‐link filamentous actin into tightly packed
parallel bundles. These bundles are important for the organization and morphology of an …