The openCARP simulation environment for cardiac electrophysiology
Abstract Background and Objective: Cardiac electrophysiology is a medical specialty with a
long and rich tradition of computational modeling. Nevertheless, no community standard for …
long and rich tradition of computational modeling. Nevertheless, no community standard for …
A review of healthy and fibrotic myocardium microstructure modeling and corresponding intracardiac electrograms
Computational simulations of cardiac electrophysiology provide detailed information on the
depolarization phenomena at different spatial and temporal scales. With the development of …
depolarization phenomena at different spatial and temporal scales. With the development of …
Using cardiac ionic cell models to interpret clinical data
For over 100 years cardiac electrophysiology has been measured in the clinic. The electrical
signals that can be measured span from noninvasive ECG and body surface potentials …
signals that can be measured span from noninvasive ECG and body surface potentials …
Effect of scar and His–Purkinje and myocardium conduction on response to conduction system pacing
Introduction Conduction system pacing (CSP), in the form of His bundle pacing (HBP) or left
bundle branch pacing (LBBP), is emerging as a valuable cardiac resynchronization therapy …
bundle branch pacing (LBBP), is emerging as a valuable cardiac resynchronization therapy …
Fibrotic remodeling during persistent atrial fibrillation: In silico investigation of the role of calcium for human atrial myofibroblast electrophysiology
During atrial fibrillation, cardiac tissue undergoes different remodeling processes at different
scales from the molecular level to the tissue level. One central player that contributes to both …
scales from the molecular level to the tissue level. One central player that contributes to both …
Using Machine Learning to Characterize Atrial Fibrotic Substrate From Intracardiac Signals With a Hybrid in silico and in vivo Dataset
J Sánchez, G Luongo, M Nothstein, LA Unger… - Frontiers in …, 2021 - frontiersin.org
In patients with atrial fibrillation, intracardiac electrogram signal amplitude is known to
decrease with increased structural tissue remodeling, referred to as fibrosis. In addition to …
decrease with increased structural tissue remodeling, referred to as fibrosis. In addition to …
Factors promoting conduction slowing as substrates for block and reentry in infarcted hearts
The development of effective and safe therapies for scar-related ventricular tachycardias
requires a detailed understanding of the mechanisms underlying the conduction block that …
requires a detailed understanding of the mechanisms underlying the conduction block that …
[HTML][HTML] Complex-order fractional diffusion in reaction-diffusion systems
A Bueno-Orovio, K Burrage - Communications in Nonlinear Science and …, 2023 - Elsevier
Fractional differential equations have become a fundamental modelling approach for
understanding and simulating the many aspects of non-locality and spatial heterogeneity of …
understanding and simulating the many aspects of non-locality and spatial heterogeneity of …
Late-gadolinium enhancement interface area and electrophysiological simulations predict arrhythmic events in patients with nonischemic dilated cardiomyopathy
Objectives This study sought to investigate whether shape-based late gadolinium
enhancement (LGE) metrics and simulations of re-entrant electrical activity are associated …
enhancement (LGE) metrics and simulations of re-entrant electrical activity are associated …
Sudden cardiac death prediction in non-ischemic dilated cardiomyopathy: a multiparametric and dynamic approach
DJ Hammersley, BP Halliday - Current cardiology reports, 2020 - Springer
Abstract Purpose of Review Sudden cardiac death is recognised as a devastating
consequence of non-ischaemic dilated cardiomyopathy. Although implantable cardiac …
consequence of non-ischaemic dilated cardiomyopathy. Although implantable cardiac …