PDGF receptor signaling networks in normal and cancer cells
JB Demoulin, A Essaghir - Cytokine & growth factor reviews, 2014 - Elsevier
For about four decades, platelet-derived growth factors (PDGF) and their receptors have
been the subject of intense research, revealing their roles in embryo development and …
been the subject of intense research, revealing their roles in embryo development and …
The guanylate-binding proteins: emerging insights into the biochemical properties and functions of this family of large interferon-induced guanosine triphosphatase
DJ Vestal, JA Jeyaratnam - Journal of Interferon & Cytokine …, 2011 - liebertpub.com
Originally identified by their unusual ability to bind guanosine monophosphate (GMP)
nucleotide agarose, the guanylate-binding proteins (GBPs) were used extensively to …
nucleotide agarose, the guanylate-binding proteins (GBPs) were used extensively to …
Determinants of GBP Recruitment to Toxoplasma gondii Vacuoles and the Parasitic Factors That Control It
S Virreira Winter, W Niedelman, KD Jensen… - PloS one, 2011 - journals.plos.org
IFN-γ is a major cytokine that mediates resistance against the intracellular parasite
Toxoplasma gondii. The p65 guanylate-binding proteins (GBPs) are strongly induced by IFN …
Toxoplasma gondii. The p65 guanylate-binding proteins (GBPs) are strongly induced by IFN …
Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner
N Britzen-Laurent, M Bauer, V Berton, N Fischer… - PloS one, 2010 - journals.plos.org
Guanylate-binding proteins (GBPs) belong to the dynamin family of large GTPases and
represent the major IFN-γ-induced proteins. Here we systematically investigated the …
represent the major IFN-γ-induced proteins. Here we systematically investigated the …
[HTML][HTML] Single cell RNA sequencing identifies an early monocyte gene signature in acute respiratory distress syndrome
Acute respiratory distress syndrome (ARDS) results from overwhelming pulmonary
inflammation. Prior bulk RNA sequencing provided limited insights into ARDS pathogenesis …
inflammation. Prior bulk RNA sequencing provided limited insights into ARDS pathogenesis …
Identification of a putative quantitative trait nucleotide in guanylate binding protein 5 for host response to PRRS virus infection
Background Previously, we identified a major quantitative trait locus (QTL) for host response
to Porcine Respiratory and Reproductive Syndrome virus (PRRSV) infection in high linkage …
to Porcine Respiratory and Reproductive Syndrome virus (PRRSV) infection in high linkage …
A new splice variant of the human guanylate‐binding protein 3 mediates anti‐influenza activity through inhibition of viral transcription and replication
A Nordmann, L Wixler, Y Boergeling… - The FASEB …, 2012 - Wiley Online Library
Guanylate‐binding proteins (GBPs) belong to the family of large GTPases that are induced
in response to interferons. GBPs contain an N‐terminal globular GTPase domain and a C …
in response to interferons. GBPs contain an N‐terminal globular GTPase domain and a C …
Interferon-inducible guanylate binding protein (GBP2) is associated with better prognosis in breast cancer and indicates an efficient T cell response
Background Recently, interferon-inducible guanylate binding protein (GBP2) has been
discussed as a possible control factor in tumor development, which is controlled by p53, and …
discussed as a possible control factor in tumor development, which is controlled by p53, and …
Guanylate-binding protein 2 regulates Drp1-mediated mitochondrial fission to suppress breast cancer cell invasion
J Zhang, Y Zhang, W Wu, F Wang, X Liu, G Shui… - Cell death & …, 2017 - nature.com
Abstract Guanylate-binding protein 2 (GBP2) is a member of the large GTPase superfamily
that is strongly induced by interferon-γ (IFN-γ). Although the biochemical characteristics of …
that is strongly induced by interferon-γ (IFN-γ). Although the biochemical characteristics of …
Gamma interferon-induced guanylate binding protein 1 is a novel actin cytoskeleton remodeling factor
N Ostler, N Britzen-Laurent, A Liebl… - … and cellular biology, 2014 - Taylor & Francis
Gamma interferon (IFN-γ) regulates immune defenses against viruses, intracellular
pathogens, and tumors by modulating cell proliferation, migration, invasion, and vesicle …
pathogens, and tumors by modulating cell proliferation, migration, invasion, and vesicle …