The prevalence of neuropsychiatric symptoms in Alzheimer's disease: systematic review and meta-analysis

QF Zhao, L Tan, HF Wang, T Jiang, MS Tan… - Journal of affective …, 2016 - Elsevier
Background Neuropsychiatric symptoms (NPS) are being increasingly recognized as
common serious problems in Alzheimer's disease (AD). However, published data on the …

Apathy in neurodegenerative diseases: recommendations on the design of clinical trials

J Cummings, JH Friedman… - Journal of geriatric …, 2015 - journals.sagepub.com
Apathy is a common feature of neurodegenerative disorders but is difficult to study in a
clinical trial setting due to practical and conceptual barriers. Principal challenges include a …

Burden of epilepsy: a prevalence-based cost of illness study of direct, indirect and intangible costs for epilepsy

L Gao, L Xia, SQ Pan, T Xiong, SC Li - Epilepsy research, 2015 - Elsevier
Objectives We aimed to gauge the burden of epilepsy in China from a societal perspective
by estimating the direct, indirect and intangible costs. Methods Patients with epilepsy and …

Apathy and attentional biases in Alzheimer's disease

SA Chau, J Chung, N Herrmann… - Journal of …, 2016 - content.iospress.com
Background: Apathy, one of the most prevalent neuropsychiatric symptoms in Alzheimer's
disease (AD), can be difficult to assess as cognition deteriorates. There is a need for more …

Diagnosis and assessment of apathy in elderly chinese patients with cerebral small vessel disease

H Zhào, Y Liu, Z Xia, H Xie, Y Huang - Frontiers in Psychiatry, 2021 - frontiersin.org
Objective: The study aimed to estimate the frequency of apathy in Chinese patients with
cerebral small vessel disease (CSVD) and investigate the relationship between apathy and …

Apathy and suicide-related ideation 3 months after stroke: a cross-sectional study

WK Tang, L Caeiro, CG Lau, H Liang, V Mok… - BMC neurology, 2015 - Springer
Background Both apathy and suicide are common in poststroke patients. However, the
association between poststroke apathy and suicide-related ideation (SI) in Chinese stroke …

Urinary AD7c-NTP Evaluates cognition impairment and differentially diagnoses AD and MCI

MR Xu, RF Dai, QQ Wei, J Wang… - American Journal of …, 2022 - journals.sagepub.com
The AD7c-NTP is a promising biomarker for AD diagnosis. However, the exact urinary AD7c-
NTP concentration to differentiate AD from the mild cognitive impairment (MCI) remains …

[HTML][HTML] Detecting apathy in patients with cerebral small vessel disease

X Cai, H Zhào, Z Li, Y Ding, Y Huang - Frontiers in Aging …, 2022 - frontiersin.org
Background: Apathy is attracting more and more attention in clinical practice. As one the
most common features of Cerebral Small Vessel Disease (CSVD), the assessment of apathy …

The relationship between apathy and nonparametric variables of rest activity rhythm in older adults with cerebral small vessel disease

H Zhao, H Li, Y Ding, Z Li, Y Huang - Chronobiology International, 2023 - Taylor & Francis
The goal of the current study was to demonstrate if the rest-activity rhythm (RAR) was altered
in apathetic older adults with cerebral small vessel disease (CSVD) and find out the …

Functional magnetic resonance imaging study of apathy in Alzheimer's disease

H Zhao, W Tang, X Xu, Z Zhao… - The Journal of …, 2014 - Am Neuropsych Assoc
An fMRI study was launched to understand mechanisms of Alzheimer's disease (AD)
patients with apathy. The authors reviewed seven AD patients with apathy and six AD …