Intrahepatic cholangiocarcinoma (iCCA) is a molecularly heterogeneous hepatobiliary
neoplasm with poor prognosis and limited therapeutic options. The incidence of this …

Background & Aims The role of 18 F-fluorodeoxyglucose positron emission tomography (18
FDG-PET) in the diagnosis and staging of patients with biliary tract cancers (BTCs) remains …

Patients with cholangiocarcinoma often present with locally advanced or metastatic disease.
There is a need for effective therapeutic strategies for advanced stage cholangiocarcinoma …

Abstract Background and Aims Macrophages are prominent components of solid tumors and
exhibit distinct functions in different tumor microenvironments. Exosomes are emerging as …

Cholangiocarcinoma (CC) is typically diagnosed at an advanced stage and is refractory to
surgical intervention and chemotherapy. Despite a global increase in the incidence of CC …

Background Biliary tract cancers are rare, aggressive neoplasms. Most patients present with
advanced/unresectable or metastatic disease at diagnosis, and no second‐line regimen has …

Background & aims Very few data are available in literature about the role of radiofrequency
ablation (RFA) in intrahepatic cholangiocarcinoma (ICC) and previous studies are mainly …

Cholangiocarcinoma (CCA) is a highly invasive cancer, diagnosed at an advanced stage,
and refractory to surgical intervention and chemotherapy. Cyclin-dependent kinases (CDKs) …

Background The role of routine lymph node dissection (LND) in the surgical treatment of
intrahepatic cholangiocarcinoma (ICC) remains controversial. The objective of this study …

Background & Aims Mucin 13 (MUC13) is reportedly overexpressed in human malignancies.
However, the clinicopathological and biological significance of MUC13 in human …