The endocannabinoid system: a potential target for the treatment of various diseases
H Lowe, N Toyang, B Steele, J Bryant… - International journal of …, 2021 - mdpi.com
The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …
balance in internal environment (temperature, mood, and immune system) and energy input …
The tempted brain eats: pleasure and desire circuits in obesity and eating disorders
What we eat, when and how much, all are influenced by brain reward mechanisms that
generate “liking” and “wanting” for foods. As a corollary, dysfunction in reward circuits might …
generate “liking” and “wanting” for foods. As a corollary, dysfunction in reward circuits might …
'Liking'and 'wanting'food rewards: brain substrates and roles in eating disorders
KC Berridge - Physiology & behavior, 2009 - Elsevier
What brain reward systems mediate motivational 'wanting'and hedonic 'liking'for food
rewards? And what roles do those systems play in eating disorders? This article surveys …
rewards? And what roles do those systems play in eating disorders? This article surveys …
The emerging role of the endocannabinoid system in endocrine regulation and energy balance
During the last few years, the endocannabinoid system has emerged as a highly relevant
topic in the scientific community. Many different regulatory actions have been attributed to …
topic in the scientific community. Many different regulatory actions have been attributed to …
Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2‐arachidonoyl glycerol
Endocannabinoids are implicated in appetite and body weight regulation. In rodents,
anandamide stimulates eating by actions at central CB1 receptors, and hypothalamic …
anandamide stimulates eating by actions at central CB1 receptors, and hypothalamic …
CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity
C Ravinet Trillou, C Delgorge, C Menet… - International journal of …, 2004 - nature.com
OBJECTIVE: There is growing evidence for an implication of the CB1 receptor subtype of the
endocannabinoid system in the regulation of eating and fat deposition. To further define the …
endocannabinoid system in the regulation of eating and fat deposition. To further define the …
Hedonic hot spots in the brain
Hedonic “liking” for sensory pleasures is an important aspect of reward, and excessive
'liking'of particular rewards might contribute to excessive consumption and to disorders such …
'liking'of particular rewards might contribute to excessive consumption and to disorders such …
Anti-obesity effect of SR141716, a CB1 receptor antagonist, in diet-induced obese mice
C Ravinet Trillou, M Arnone… - American Journal …, 2003 - journals.physiology.org
Because the CB1 receptor antagonist SR141716 was previously reported to modulate food
intake in rodents, we studied its efficacy in reducing obesity in a diet-induced obesity (DIO) …
intake in rodents, we studied its efficacy in reducing obesity in a diet-induced obesity (DIO) …
Liking vs. wanting food: importance for human appetite control and weight regulation
G Finlayson, N King, JE Blundell - Neuroscience & Biobehavioral Reviews, 2007 - Elsevier
Current train of thought in appetite research is favouring an interest in non-homeostatic or
hedonic (reward) mechanisms in relation to overconsumption and energy balance. This …
hedonic (reward) mechanisms in relation to overconsumption and energy balance. This …
Ligands that target cannabinoid receptors in the brain: from THC to anandamide and beyond
RG Pertwee - Addiction biology, 2008 - Wiley Online Library
ABSTRACT A major finding—that (–)‐trans‐Δ9‐tetrahydrocannabinol (Δ9‐THC) is largely
responsible for the psychotropic effects of cannabis—prompted research in the 1970s and …
responsible for the psychotropic effects of cannabis—prompted research in the 1970s and …