Directed evolution is a form of artificial selection that has been used for decades to find
biomolecules and organisms with new or enhanced functional traits. Directed evolution can …

Microbial consortia are ubiquitous in nature, in which multiple microbial species cooperate
to complete some important tasks such as lignocellulose degradation. Because of the …

Powerful distributed computing can be achieved by communicating cells that individually
perform simple operations. Here, we report design software to divide a large genetic circuit …

The rational design and implementation of synthetic mammalian communication systems
can unravel fundamental design principles of cell communication circuits and offer a …

Engineered consortia are a major research focus for synthetic biologists because they can
implement sophisticated behaviors inaccessible to single-strain systems. However, this …

Microbial consortia exhibit spatial patterning across diverse environments. Since probing the
self-organization of natural microbial communities is limited by their inherent complexity …

Bacteria can organise themselves into communities in the forms of biofilms and swarms.
Through chemical and physical interactions between cells, these communities exhibit …

Biological computing is a promising field with potential applications in biosafety,
environmental monitoring, and personalized medicine. Here we present work on the design …

The measurement of gene expression using fluorescence markers has been a cornerstone
of synthetic biology for the past two decades. However, the use of arbitrary units has limited …

Biological systems often need to operate in complex environments where conditions can
rapidly change. This is possible because of their inherent ability to sense changes and …