[HTML][HTML] mRNA-based therapeutics: powerful and versatile tools to combat diseases

S Qin, X Tang, Y Chen, K Chen, N Fan… - Signal transduction and …, 2022 - nature.com
The therapeutic use of messenger RNA (mRNA) has fueled great hope to combat a wide
range of incurable diseases. Recent rapid advances in biotechnology and molecular …

[HTML][HTML] Systematic review and meta-analysis of the effectiveness and perinatal outcomes of COVID-19 vaccination in pregnancy

S Prasad, E Kalafat, H Blakeway, R Townsend… - Nature …, 2022 - nature.com
Safety and effectiveness of COVID-19 vaccines during pregnancy is a particular concern
affecting vaccination uptake by this vulnerable group. Here we evaluated evidence from 23 …

Association between mRNA vaccination and COVID-19 hospitalization and disease severity

MW Tenforde, WH Self, K Adams, M Gaglani, AA Ginde… - Jama, 2021 - jamanetwork.com
Importance A comprehensive understanding of the benefits of COVID-19 vaccination
requires consideration of disease attenuation, determined as whether people who develop …

[HTML][HTML] SARS-CoV-2 infection and COVID-19 vaccination rates in pregnant women in Scotland

SJ Stock, J Carruthers, C Calvert, C Denny… - Nature medicine, 2022 - nature.com
Population-level data on COVID-19 vaccine uptake in pregnancy and SARS-CoV-2 infection
outcomes are lacking. We describe COVID-19 vaccine uptake and SARS-CoV-2 infection in …

Association of BNT162b2 COVID-19 vaccination during pregnancy with neonatal and early infant outcomes

I Goldshtein, DM Steinberg, J Kuint, G Chodick… - JAMA …, 2022 - jamanetwork.com
Importance Pregnant women were excluded from the BNT162b2 messenger RNA (mRNA)
COVID-19 vaccine (Pfizer-BioNTech) preauthorization trial. Therefore, observational data on …

[HTML][HTML] COVID-19 vaccination in pregnancy, paediatrics, immunocompromised patients, and persons with history of allergy or prior SARS-CoV-2 infection: overview …

N Luxi, A Giovanazzi, A Capuano, S Crisafulli… - Drug safety, 2021 - Springer
To date, four vaccines have been authorised for emergency use and under conditional
approval by the European Medicines Agency to prevent COVID-19: Comirnaty, COVID-19 …

Association of COVID-19 vaccination in pregnancy with adverse peripartum outcomes

DB Fell, T Dhinsa, GD Alton, E Török, S Dimanlig-Cruz… - Jama, 2022 - jamanetwork.com
Importance There is limited comparative epidemiological evidence on outcomes associated
with COVID-19 vaccination during pregnancy; monitoring pregnancy outcomes in large …

[HTML][HTML] Maternal immune response and placental antibody transfer after COVID-19 vaccination across trimester and platforms

CG Atyeo, LL Shook, S Brigida, RM De Guzman… - Nature …, 2022 - nature.com
The availability of three COVID-19 vaccines in the United States provides an unprecedented
opportunity to examine how vaccine platforms and timing of vaccination in pregnancy impact …

Newborn and early infant outcomes following maternal COVID-19 vaccination during pregnancy

SCJ Jorgensen, SSM Drover, DB Fell, PC Austin… - JAMA …, 2023 - jamanetwork.com
Importance The study team previously showed that maternal mRNA COVID-19 vaccination
during pregnancy confers protection against SARS-CoV-2 infection and COVID-19–related …

Maternal and neonatal SARS-CoV-2 immunoglobulin G antibody levels at delivery after receipt of the BNT162b2 messenger RNA COVID-19 vaccine during the …

N Kugelman, C Nahshon, P Shaked-Mishan… - JAMA …, 2022 - jamanetwork.com
Importance BNT162b2 messenger RNA (mRNA) COVID-19 vaccination in the third trimester
was found to be associated with a strong maternal humoral IgG response that crossed the …