Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease

Z Chen, R Tian, Z She, J Cai, H Li - Free Radical Biology and Medicine, 2020 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver
disease worldwide and is strongly associated with the presence of oxidative stress …

[PDF][PDF] Epidemiological features of NAFLD from 1999 to 2018 in China

J Zhou, F Zhou, W Wang, XJ Zhang, YX Ji… - …, 2020 - Wiley Online Library
With dramatic changes in lifestyles over the last 20 years, nonalcoholic fatty liver disease
(NAFLD) has become the most prevalent liver disorder in China but has not received …

[HTML][HTML] CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing

H Zeng, H Qin, M Liao, E Zheng, X Luo, A Xiao, Y Li… - Molecular …, 2022 - Elsevier
Objective Enhanced de novo lipogenesis (DNL) in hepatocytes is a major contributor to
nonalcoholic fatty liver disease (NAFLD). Fatty acid translocase (FAT/CD36) is involved in …

[HTML][HTML] Noninvasive evaluation of nonalcoholic fatty liver disease: Current evidence and practice

JH Zhou, JJ Cai, ZG She, HL Li - World journal of gastroenterology, 2019 - ncbi.nlm.nih.gov
With the increasing number of individuals with diabetes and obesity, nonalcoholic fatty liver
disease (NAFLD) is becoming increasingly prevalent, affecting one-quarter of adults …

Supervised machine learning models for liver disease risk prediction

E Dritsas, M Trigka - Computers, 2023 - mdpi.com
The liver constitutes the largest gland in the human body and performs many different
functions. It processes what a person eats and drinks and converts food into nutrients that …

Nonalcoholic fatty liver disease: an emerging driver of hypertension

YC Zhao, GJ Zhao, Z Chen, ZG She, J Cai, H Li - Hypertension, 2020 - Am Heart Assoc
Hypertension, a multifactorial disorder resulting from the interplay between genetic
predisposition and environmental risk factors, affects≈ 30% of adults. Emerging evidence …

Insights into the epidemiology, pathogenesis, and therapeutics of nonalcoholic fatty liver diseases

Y Yu, J Cai, Z She, H Li - Advanced Science, 2019 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease which affects≈
25% of the adult population worldwide, placing a tremendous burden on human health. The …

[PDF][PDF] The role of innate immune cells in nonalcoholic steatohepatitis

J Cai, XJ Zhang, H Li - Hepatology, 2019 - Wiley Online Library
Inflammation and metabolic dysfunction are hallmarks of nonalcoholic steatohepatitis
(NASH), which is one of the fastest‐growing liver diseases worldwide. Emerging evidence …

Nonalcoholic fatty liver disease: an emerging driver of cardiac arrhythmia

ZE Chen, J Liu, F Zhou, H Li, XJ Zhang… - Circulation …, 2021 - Am Heart Assoc
Cardiac arrhythmias and the resulting sudden cardiac death are significant cardiovascular
complications that continue to impose a heavy burden on patients and society. An emerging …

[HTML][HTML] Reactive oxygen species and oxidative stress in the pathogenesis of MAFLD

K Clare, JF Dillon, PN Brennan - Journal of Clinical and …, 2022 - ncbi.nlm.nih.gov
The pathogenesis of metabolic-associated fatty liver disease (MAFLD) is complex and
thought to be dependent on multiple parallel hits on a background of genetic susceptibility …