Carotid body chemoreceptors: physiology, pathology, and implications for health and disease
R Iturriaga, J Alcayaga, MW Chapleau… - Physiological …, 2021 - journals.physiology.org
The carotid body (CB) is the main peripheral chemoreceptor for arterial respiratory gases O2
and CO2 and pH, eliciting reflex ventilatory, cardiovascular, and humoral responses to …
and CO2 and pH, eliciting reflex ventilatory, cardiovascular, and humoral responses to …
Cardiac innervation and sudden cardiac death
K Fukuda, H Kanazawa, Y Aizawa, JL Ardell… - Circulation …, 2015 - Am Heart Assoc
Afferent and efferent cardiac neurotransmission via the cardiac nerves intricately modulates
nearly all physiological functions of the heart (chronotropy, dromotropy, lusitropy, and …
nearly all physiological functions of the heart (chronotropy, dromotropy, lusitropy, and …
[HTML][HTML] Regulation of breathing and autonomic outflows by chemoreceptors
PG Guyenet - Comprehensive Physiology, 2014 - ncbi.nlm.nih.gov
Lung ventilation fluctuates widely with behavior but arterial PCO 2 remains stable. Under
normal conditions, the chemoreflexes contribute to PaCO 2 stability by producing small …
normal conditions, the chemoreflexes contribute to PaCO 2 stability by producing small …
The sympathetic/parasympathetic imbalance in heart failure with reduced ejection fraction
JS Floras, P Ponikowski - European heart journal, 2015 - academic.oup.com
Cardiovascular autonomic imbalance, a cardinal phenotype of human heart failure, has
adverse implications for symptoms during wakefulness and sleep; for cardiac, renal, and …
adverse implications for symptoms during wakefulness and sleep; for cardiac, renal, and …
Neural regulation of cardiovascular response to exercise: role of central command and peripheral afferents
ACL Nobrega, DO′ Leary, BM Silva… - BioMed research …, 2014 - Wiley Online Library
During dynamic exercise, mechanisms controlling the cardiovascular apparatus operate to
provide adequate oxygen to fulfill metabolic demand of exercising muscles and to guarantee …
provide adequate oxygen to fulfill metabolic demand of exercising muscles and to guarantee …
Device-based therapies for arterial hypertension
L Lauder, M Azizi, AJ Kirtane, M Boehm… - Nature Reviews …, 2020 - nature.com
Arterial hypertension is the most prevalent modifiable risk factor associated with
cardiovascular morbidity and mortality. Although antihypertensive drugs are widely …
cardiovascular morbidity and mortality. Although antihypertensive drugs are widely …
The autonomic nervous system as a therapeutic target in heart failure: a scientific position statement from the Translational Research Committee of the Heart Failure …
M Van Bilsen, HC Patel, J Bauersachs… - European journal of …, 2017 - Wiley Online Library
Despite improvements in medical therapy and device‐based treatment, heart failure (HF)
continues to impose enormous burdens on patients and health care systems worldwide …
continues to impose enormous burdens on patients and health care systems worldwide …
Translational neurocardiology: preclinical models and cardioneural integrative aspects
JL Ardell, MC Andresen, JA Armour… - The Journal of …, 2016 - Wiley Online Library
Neuronal elements distributed throughout the cardiac nervous system, from the level of the
insular cortex to the intrinsic cardiac nervous system, are in constant communication with …
insular cortex to the intrinsic cardiac nervous system, are in constant communication with …
Physiology of the carotid body: from molecules to disease
P Ortega-Sáenz, J López-Barneo - Annual review of physiology, 2020 - annualreviews.org
The carotid body (CB) is an arterial chemoreceptor organ located in the carotid bifurcation
and has a well-recognized role in cardiorespiratory regulation. The CB contains …
and has a well-recognized role in cardiorespiratory regulation. The CB contains …
Carotid body denervation improves autonomic and cardiac function and attenuates disordered breathing in congestive heart failure
Key points A strong correlation between disordered breathing patterns, elevated
sympathetic nerve activity and enhanced chemoreflex sensitivity exists in patients with heart …
sympathetic nerve activity and enhanced chemoreflex sensitivity exists in patients with heart …