This review provides an overview on the development of Multiple sequence alignment
(MSA) methods and their main applications. It is focused on progress made over the past …

This review focuses on recent trends in multiple sequence alignment tools. It describes the
latest algorithmic improvements including the extension of consistency-based methods to …

Here, we describe a web server that integrates structural alignments with the MAFFT
multiple sequence alignment (MSA) tool. For this purpose, we have prepared a web-based …

This article introduces a new interface for T-Coffee, a consistency-based multiple sequence
alignment program. This interface provides an easy and intuitive access to the most popular …

Understanding how protein structures and functions have diversified is a central goal in
molecular evolution. Surveys of very divergent proteins from model organisms, however, are …

An ever-increasing number of biological modeling methods depend on the assembly of an
accurate multiple sequence alignment (MSA). These include phylogenetic trees, profiles …

As a result of advancements in high-throughput technology, the sequencing of the
pioneering 16S rRNA gene marker is gradually shedding light on the taxonomic …

Multiple protein sequence alignment methods are central to many applications in molecular
biology. These methods are typically assessed on benchmark datasets including BALIBASE …

Motivation Protein sequence alignments are essential to structural, evolutionary and
functional analysis, but their accuracy is often limited by sequence similarity unless …

Protein structure is conserved beyond sequence, making multiple structural alignment
(MSTA) essential for analyzing distantly related proteins. Computational prediction methods …