We generated a library of~ 1000 Drosophila stocks in which we inserted a construct in the
intron of genes allowing expression of GAL4 under control of endogenous promoters while …

The genome versus experience dichotomy has dominated understanding of behavioral
individuality. By contrast, the role of nonheritable noise during brain development in …

Phagocytic clearance of degenerating dendrites or axons is critical for maintaining tissue
homeostasis and preventing neuroinflammation. Externalized phosphatidylserine (PS) has …

During animal development, the spatiotemporal properties of molecular events largely
determine the biological outcomes. Conventional gene analysis methods lack the …

Stereotypic dendrite arborizations are key morphological features of neuronal identity, as the
size, shape and location of dendritic trees determine the synaptic input fields and how …

Sensing environmental cues requires well-built neuronal circuits linked to the body surface.
Sensory neurons generate dendrites to innervate surface epithelium, thereby making it the …

During neuronal pruning, phagocytes engulf shed cellular debris to avoid inflammation and
maintain tissue homeostasis. How phagocytic receptors recognize degenerating neurites …

After injury, severed dendrites and axons expose the “eat-me” signal phosphatidylserine
(PS) on their surface while they break down. The degeneration of injured axons is controlled …

The CRISPR/Cas9 gene editing system continues to push the boundaries of genetic
analysis. Here, papers from Farboud, Severson, and Meyer and Poe et al. describe cutting …

Live imaging approaches are essential for monitoring how neurons go through a
coordinated series of differentiation steps in their native mechanical and chemical …