Microbes form surface-adherent community structures called biofilms and these biofilms play
a critical role in infection. Biofilms impart antibiotic resistance and sometimes become …

The human intestinal tract harbors a profound variety of microorganisms that live in
symbiosis with the host and each other. It is a complex and highly dynamic environment …

Development of effective therapies to control oral biofilms is challenging, as topically
introduced agents must avoid rapid clearance from biofilm–tooth interfaces while targeting …

Background Staphylococcus aureus and Pseudomonas aeruginosa are major pathogens in
chronic rhinosinusitis (CRS) and their biofilms have been associated with poorer …

We previously reported on cationic, pH-responsive p (DMAEMA)-bp (DMAEMA-co-BMA-co-
PAA) block copolymer micelles with high affinity for dental and biofilm surfaces and efficient …

As our knowledge of host-microbial interactions within the oral cavity increases, future
treatments are likely to be more targeted. For example, efforts to target a single species or …

Open fractures and internal fixation implants are often accompanied by bacterial infection,
leading to osteomyelitis, characterized by intractable bone infection and sequestrum …

Dental caries is one of the most prevalent non-communicable diseases worldwide, mediated
by a multispecies biofilm that consists of high levels of acidogenic bacteria which ferment …

Nanotechnology has been revealed as a fundamental approach for antibiotics delivery. In
this paper, recent findings demonstrating the superiority of nanocarried-antibiotics over …

The spontaneous healing of critical-sized bone defects is often limited, posing an increased
risk of complications and suboptimal outcomes. Osteogenesis, a complex process central to …